Bone and Connective Tissue
Diseases of bone (such as osteoporosis) and connective tissue (rheumatoid arthritis, lupus) can be studied in cell and animal models with small molecules that regulate immunity, inflammation, protein folding, and certain key kinases like JAK.
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1,4-DPCA | Prolyl hydroxylase inhibitor
From $42.00CAS:331830-20-7Catalog Number:10-2956Activity:Prolyl hydroxylase inhibitorChemical Name:1,4-Dihydrophenonthrolin-4-one-3-carboxylic acidMolecular Weight:240.22Molecular Formula:C13H8N2O3Solubility:Soluble in DMSO (up to 15 mg/ml with warming).Physical Properties:Off-white solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.Shipping Code:RT -
20(S)-Hydroxycholesterol | Smoothened activator
From $40.00CAS:516-72-3Catalog Number:10-4540Activity:Smoothened activatorChemical Name:5-Cholesten-3β, 20α-diolMolecular Weight:402.66Molecular Formula:C27H46O2Solubility:Soluble in DMSO or in Ethanol.Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT -
Ansatrienin B | Cytotoxic activity
From $100.00CAS:82189-04-6Catalog Number:10-1576Activity:Cytotoxic activityAlternate Names:Mycotrienin II; Antibiotic T2311Source:Fermentation product from Streptomyces sp.Molecular Weight:638.87Molecular Formula:C36H50N2O8Solubility:Soluble in DMSO, DMF, Ethanol or MethanolPhysical Properties:Pale-yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO, DMF, ethanol, or methanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
BADGE | PPAR gamma antagonist
From $30.00CAS:1675-54-3Catalog Number:10-2618Activity:PPARγ antagonistChemical Name:2,3-Bis[4-(2,3-epoxypropoxy)phenyl]propaneAlternate Names:Bisphenol A diglycidyl etherMolecular Weight:340.41Molecular Formula:C21H24O4Solubility:Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 15 mg/ml)Physical Properties:White low melting point solidPurity:95% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT -
Clodronate 2Na | Induces osteoclast apoptosis
From $30.00CAS:88416-50-6Catalog Number:10-4631Activity:Induces osteoclast apoptosisChemical Name:Dichloromethylenediphosphonic acid disodium tetrahydrateMolecular Weight:360.92Molecular Formula:CH2Cl2O6P2·2Na·4H2OSolubility:Soluble in Water (up to at least 10 mg/ml)Physical Properties:White solidPurity:98%
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.Shipping Code:RT -
DY131 | Estrogen-related receptor ERRbeta and ERRgamma agonist
From $42.00CAS:95167-41-2Catalog Number:10-1561Activity:Estrogen-related receptor ERRbeta and ERRgamma agonistChemical Name:N-(4-(Diethylaminobenzylidenyl)-N’-(4-hydroxybenzoyl)-hydrazineAlternate Name:GSK-9089Molecular Weight:311.38Molecular Formula:C18H21N3O2Solubility:Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 8 mg/ml with warming).Physical Properties:Yellow solidPurity:98% by TLCNMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.Shipping Code:RT
