BAY K8644 | L-type calcium channel activator

CAS:
71145-03-4
Catalog Number:
10-4518
Activity:
L-type calcium channel activator
Chemical Name:
(±)- Methyl 1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylate
Molecular Weight:
356.3
Molecular Formula:
C16H15F3N2O4
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
Physical Properties:
Yellow solid
Purity:
>98% by TLC
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
5 mg$65.00
25 mg$250.00

BAY K8644 (71145-03-4) is an L-type Ca2+-channel activator with positive inotropic and vasoconstrictive effects.1-4

References/Citations:

1) Schramm et al. (1983) Novel Dihydropyridines with positive inotropic action through activation of Ca2+ channels; Nature, 303 535
2) Yamamoto et al. (1984) Bay K8644 Differentiates between potential and receptor operated Ca2+ channels; Eur. J. Pharmacol. 102 555
3) Thomas et al. (1985) A dihydropyridine (Bay K 8644) that enhances calcium currents in guinea pig and calf myocardial cells. A new type of positive inotropic agent; Circ. Res., 56 87
4) Shi et al. (2009) Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small molecule compounds; Cell Stem Cell, 3 568

CAS:
71145-03-4
Catalog Number:
10-4518
Activity:
L-type calcium channel activator
Chemical Name:
(±)- Methyl 1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylate
Molecular Weight:
356.3
Molecular Formula:
C16H15F3N2O4
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
Physical Properties:
Yellow solid
Purity:
>98% by TLC
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee