my account
  Loading... Please wait...


Sort by
  • Focus Biomolecules cell signaling reagent supplier, chemical structure of FLUO-8 (AM) | Cellular calcium probe
    FLUO-8 (AM) is a cell-permeable acetoxymethyl (AM) ester derivative of Fluo-8. Approximately twice as bright as Fluo-4. Absorbance 452 nm (26,000); Emission 515 nm (after AM hydrolysis; dissolved in 10 mM EGTA, 100 mM KCl,...

  • Focus Biomolecules cell signaling reagent supplier, structure KB-R7943 mesylate | TRPC channel blocker | CAS 182004-65-5
    KB-R7943 (182004-65-5) is a potent and selective inhibitor of the reversed Na+/Ca2+ exchanger (NCE or NCX; IC50's = 1.2-2.4 μM in cardiomyocytes, smooth muscle cells, NCX1-transfected fibroblasts1; 0.7 μM in cultured...

  • m-3M3FBS | Phospholipase C activator
    m-3M3FBS (200933-14-8) is an activator of phospholipase C (PLC). Stimulates superoxide generation, Ca2+ release and inositol phosphate release in a variety of cell types1. Inhibits growth of U937 and THP-1 cells2. m-3M3FBS...

  • N-Acetyl-S-farnesyl-L-cysteine | S-Farnesylcysteine methyl transferase inhibitor
    N-Acetyl-S-farnesyl-L-cysteine (AFC) (135304-07-3) inhibits S-farnesylcysteine methyl transferase (Km = 20 µM).1 AFC blocked capacitative Ca2+ influx in human embryonic kidney 293 cells2 and store-regulated Ca2+ entry...

  • Focus Biomolecules cell signaling reagent supplier, structure of SKF-96365 | TRPC channel blocker | CAS 130495-35-1
    SKF-96365 (130495-35-1) is an inhibitor of receptor-mediated calcium entry (RMCE) with IC50's of 8.5 μM for ADP stimulated platelets and 11.7 μM for thrombin stimulated platelets. Also inhibits Voltage-gated Ca2+ but...

  • Sphingosine-1-phosphate | EDG receptor ligand
    Sphingosine-1-phosphate (26993-30-6) is an endogenous sphingolipid metabolite known to be involved in many cellular responses including angiogenesis, vascular maturation, cardiac development and immunity. These effects are...

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

Connect with Focus