Modify Search
Select all
Products
Pages
Posts
Modify Search
Select all
Products
Pages
Posts

C-178 | STING Antagonist

CAS:
329198-87-0
Catalog Number:
10-4131
Activity:
STING Antagonist
Chemical Name:
N-3-Dibenzofuranyl-5-nitrofuran-2-carboxamide
Molecular Weight:
322.28
Molecular Formula:
C17H10N2O5
Solubility:
Soluble in DMSO (up to 25 mg/ml)
Physical Properties:
Orange solid
Purity:
98%
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

C-178 (329198-87-0) is an inhibitor of the signaling molecule STING in mouse cells. It covalently binds to Cys91 of STING preventing activation via blockade of palmitoylation at Cys91.

References/Citations:

1) Haag et al. (2018), Targeting STING with covalent small-molecule inhibitors; Nature 559 269

C-178 | STING Antagonist is also available in the Cellular Metabolism Library.
CAS:
329198-87-0
Catalog Number:
10-4131
Activity:
STING Antagonist
Chemical Name:
N-3-Dibenzofuranyl-5-nitrofuran-2-carboxamide
Molecular Weight:
322.28
Molecular Formula:
C17H10N2O5
Solubility:
Soluble in DMSO (up to 25 mg/ml)
Physical Properties:
Orange solid
Purity:
98%
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Data Sheet:

Product Data Sheet:

Add to Quote

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee