Metastasis
Showing all 12 results
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New Products
Bosutinib | Dual Src/Abl kinase inhibitor
Bosutinib (380843-75-4) is an ATP-competitive dual Src/Abl kinase inhibitor (IC50 = 1 nM).1 It potently inhibits the apoptosis-linked STE20 kinase...$40.00 – $140.00 Select options -
New Products
C-DIM 8 | Nur77 Antagonist
C-DIM 8 (151358-47-3) is an antagonist of the orphan nuclear receptor Nur77 (NR4A1, TR3).1 Induces reactive oxygen species and ER stress in pancrea...$40.00 – $150.00 Select options -
Antioxidants
Carnosic acid | Antioxidant
Carnosic acid (3650-09-7) is an antioxidant and free radical scavenger. Increases cellular levels of glutathione (GSH) and prevents 6-hydroxydopami...$40.00 – $150.00 Select options -
Cancer
CL-82198 | MMP-13 inhibitor
CL-82198 (307002-71-7) is a selective inhibitor of MMP-13 (IC50 = 10 μM). It displayed no activity against MMP-1, MMP-9 or TACE. References/Cita...$50.00 – $200.00 Select options -
Approved Drugs
Dasatinib | Src and Bcr/Abl inhibitor
Dasatinib (302962-49-8) inhibits Src, Bcl/Abl and Lyn tyrosine kinases (IC50= 0.55, 3.0 and 8.5 nM respectively).1,2 Suppresses invasion and induce...$50.00 – $95.00 Select options -
Cancer
FH-535 | Wnt/beta-cantenin inhibitor
FH-535 (108409-83-2) suppresses Wnt/β-catenin signaling. It antagonizes PPARγ and PPARδ ligand-dependent activation which is mediated by inhibition...$50.00 – $200.00 Select options -
Alzheimers
FPS-ZM1 | RAGE receptor antagonist
FPS-ZM1 (945714-67-0) is a high-affinity RAGE (Receptor for Advanced Glycation End products) receptor antagonist (IC50 = 0.6 μM). It lowers levels ...$55.00 – $225.00 Select options -
Cancer
Napabucasin | STAT3 inhibitor / Cancer cell stemness inhibitor
Napabucasin (83280-65-3) inhibits gene transcription driven by STAT3. Inhibits cancer cell stemness gene expression and blocks spherogenesis of ste...$58.00 – $250.00 Select options -
Akt/PI3K
NSC-47924 | PHLP phosphatase inhibitor / Laminin inhibitor
NSC-47924 (6638-24-0) is a potent inhibitor of the Leucine-rich repeat protein phosphatase (PHLPP) an enzyme which is a negative regulator of Akt a...$60.00 – $200.00 Select options -
Cancer
P0180 | PRL-3 phosphatase inhibitor
P0108 (893449-38-2) is a potent inhibitor of phosphatase of regenerating liver-3 (PRL-3), IC50=0.9 μM.1 Reduces the invasive properties of mouse m...$60.00 – $240.00 Select options -
Approved Drugs
Zoledronic acid | Inhibitor of bone resorption
Zoledronic acid (118072-93-8) is a potent inhibitor of bone resorption (IC50 = 2 nM in mouse calvarial cultures).1 The mechanism of its action is t...$45.00 – $125.00 Select options -
Cancer
α-Mangostin | STING agonist (human)
α-Mangostin (6147-11-1) is a xanthone natural product that has historically been used in traditional folk medicine.1 It is a potent agonist of huma...$45.00 – $150.00 Select options
