Other Cancer
Showing 1–12 of 53 results
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Cancer
17-GMP-APA-GA | Modified Geldanamycin
17-GMP-APA-GA is an analog of geldanamycin (Cat.# 10-1084) equipped with linker for coupling to proteins or antibodies for the preparation of immun...$140.00 – $500.00 Select options -
New Products
AE 51310 | OPN4/melanopsin antagonist
AE 51310 (433966-92-8) is a potent antagonist of the GPCR OPN4/melanopsin (Ki = 0.096 nM human OPN4).1 OPN4 regulates circadian rhythms, pupil func...$50.00 – $195.00 Select options -
Cancer
AG-1517 HCl | EGFR kinase inhibitor
AG-1517 HCl (153436-54-5) is an ultra-potent inhibitor of epidermal growth factor receptor tyrosine kinase (EGFR), with an IC50 of 25 pM. Inhibits ...$70.00 – $290.00 Select options -
Apoptosis
Amifostine | Cellular protectant
Amifostine (20537-88-6) is a broad spectrum radio- and chemoprotective agent.1 Prevents chemotherapy-induced apoptosis, upregulates HIF-1α and rest...$56.00 – $224.00 Select options -
New Products
Aprepitant | NK-1 antagonist
Aprepitant (170729-80-3) is a potent human neurokinin-1 (NK-1) antagonist.1 It is an FDA approved medication for the treatment of chemotherapy-ind...$40.00 – $130.00 Select options -
Cancer
Batimastat | Matrix metalloprotease inhibitor (pan-specific)
Batimastat (130370-60-4) is a potent, broad spectrum MMP inhibitor (IC50 =3, 4, 4, 6 and 20 nM for MMPs -1, -2, -9, -7 and -3 respectively). Exhibi...$52.00 – $150.00 Select options -
New Products
BMH-21 | RNA Polymerase I inhibitor
BMH-21 (896705-16-1) is a planar heterocyclic DNA intercalator that inhibits RNA polymerase I (Pol I), IC50 = 0.6 µM in U2OS cells, but not Pols II...$52.00 – $210.00 Select options -
Cancer
C-DIM 12 | Nurr1 activator; NFkB inhibitor
C-DIM 12 (178946-89-9) activates the orphan nuclear receptor Nurr1 and inhibits bladder cancer growth.1,2 Nurr1 is a suppressor of NFkB-related neu...$55.00 – $180.00 Select options -
Cancer
Cantharidin | Phosphatase PP2A inhibitor
Cantharidin (56-25-7) inhibits protein phosphatase 2A (Ki=0.19 μM) and PP1 (Ki=1.1 μM).1 Displays >500-fold selectivity over PP2B. Suppresses gr...$40.00 – $100.00 Select options -
New Products
CB-103 | Notch signaling pathway inhibitor
CB-103 (218457-67-1) is an orally active inhibitor of the Notch signaling activation complex (IC50’s from 0.9 to 3.9 µM in various cell-based assay...$40.00 – $95.00 Select options -
Cancer
Cyclopamine | Inhibits hedgehog signaling
Cyclopamine (4449-51-8) is a naturally occurring steroidal alkaloid with teratogenic activity. Blocks sonic hedgehog signaling by binding to smooth...$56.00 – $140.00 Select options -
New Products
Deferasirox | Iron Chelator
Deferasirox (201530-41-8) is a clinically useful iron chelator used in long term care of ß-thalassemia and other heavily transfused hematological p...$50.00 – $135.00 Select options
