Cancer
Angiogenesis Autophagy Carcinogenesis Cell Cycle Cellular Stress Chemotherapeutics Cytoskeleton DNA Damage Drug resistance Epigenetics Growth factors Immunoconjugates Immunology Kinases Metabolism Metastasis Other Cancer p53 Programmed cell death Stem Cells Ubiquitin proteasome Inflammation
Showing 37–48 of 501 results
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Cancer
AG-879 | NGFR kinase inhibitor
AG-879 (148741-30-4) inhibits NGF-induced neurite growth in PC12 cells via selective inhibition of NGF receptor(pp140c-trk) autophosphorylation (IC...$70.00 – $280.00 Select options -
Cancer
AGI-5198 | R132 mutant isocitrate dehydrogenase inhibitor
AGI-5198 (135526-35-0) is a potent (IC50 = 70 nM) inhibitor of mutant isocitrate dehydrogenase 1(IDH1).1 It is selective for the R132H-IDH1 mutant...$40.00 – $95.00 Select options -
ALK
Alectinib | Potent and selective ALK inhibitor
Alectinib (1256580-46-7) is a potent (IC50 = 1.9 nM) and highly selective ALK inhibitor.1 It blocked phosphorylation of both native ALK and the L11...$60.00 – $205.00 Select options -
Aurora kinase
Alisertib | Potent and selective inhibitor of Aurora A / Destabilizes Myc
Alisertib (MLN8237, 1028486-01-2) is a highly selective and potent (IC50 = 1 nM) cell permeable inhibitor of Aurora A with off-target binding at GA...$60.00 – $230.00 Select options -
Apoptosis
Amifostine | Cellular protectant
Amifostine (20537-88-6) is a broad spectrum radio- and chemoprotective agent.1 Prevents chemotherapy-induced apoptosis, upregulates HIF-1α and rest...$56.00 – $224.00 Select options -
Cancer
Anacardic Acid | HAT inhibitor
Anacardic acid (16611-84-0) is a natural product found in cashew nut oil. It is an inhibitor of the histone acetyltransferases p300 and PCAF (IC50...$35.00 – $140.00 Select options -
Alzheimers
Anle138b | Protein aggregation inhibitor
Anle138b (882697-00-9) is an aggregation inhibitor that modulates the formation of pathological oligomers of both prion and α-synuclein.1 In mouse ...$55.00 – $195.00 Select options -
Apoptosis
Ansamitocin P3 | Microtubule depolymerizer
Ansamitocin P3 (66547-09-9) is a fungal metabolite from Actinosynnema pretiosum which binds to the phomopsin A/rhizoxin site on tubulin.1,2 Ansamit...$50.00 – $120.00 Select options -
Bone and Connective Tissue
Ansatrienin B | Cytotoxic activity
Ansatrienin b (82189-04-6) represents a novel class of ansamycins.1 Inhibits osteoclastic bone resorption.2 Potentiates the activity of several cli...$100.00 – $360.00 Select options -
Apoptosis
Aphidicolin | DNA polymerase inhibitor
Aphidicolin (38966-21-1) specifically inhibits DNA polymerase α and δ via binding to the enzyme, in eukaryotic cells such as the HeLa cell line, wi...$70.00 – $280.00 Select options -
Antifungals
Apicidin | HDAC inhibitor
Apicidin (183506-66-3) is a fungal toxin that is a potent, cell permeable inhibitor of histone deacetylases (HDAC's).1 It also displays antitumor p...$55.00 – $220.00 Select options -
Angiogenesis
Apigenin | Protein kinase inhibitor
Apigenin (520-36-5) is a plant flavonoid with antioxidant properties. It has been reported to have myriad effects on biochemical pathways including...$36.00 – $130.00 Select options
