Cardiovascular
Angiogenesis Arrhythmia Atherosclerosis Heart Failure Hypertension Ischemia Lipid Metabolism Cardioprotection Stem Cells Thrombosis
Showing 1–12 of 102 results
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Cardiovascular
1-EBIO | K+ channel activator; Promotes cardiomyocyte differentiation
1-EBIO (10045-45-1) is a direct activator of small-conductance Ca2+-activated K+ channels (SK) which dose-dependently relaxes rat mesenteric vessel...$40.00 – $148.00 Select options -
New Products
1G244 | DPP8/9 inhibitor
1G244 (847928-32-9) is a potent and selective inhibitor of the prolyl dipeptidases DPP8 (IC50 = 14 nM) and DPP9 (IC50 = 53 nM).1,2 It does not inh...$70.00 – $270.00 Select options -
Atherosclerosis
5alpha,6alpha-Epoxycholesterol | LXR ligand
5α,6α-Epoxycholesterol (1250-95-9) is a naturally occurring metabolite of cholesterol. It is a major oxysterol found in processed food1 and has be...$25.00 – $85.00 Select options -
Cardiovascular
6BIO | GSK-3 inhibitor
6BIO (667463-62-9) is a potent and selective inhibitor of glycogen synthase kinase-3 (GSK-3) IC50=5 nM.1 The first pharmacological agent shown to m...$65.00 – $260.00 Select options -
Cardioprotection
AA147 | ATF6 activator
AA147 (393121-74-9) is a preferential activator of the ER stress sensing protein ATF6.1 It was able to selectively reduce secretion and extracellul...$70.00 – $275.00 Select options -
AMPK
AICAR | AMPK activator
AICAR (2627-69-2) activates AMP-activated protein kinase (AMPK). Promotes ligand-independent activation of the insulin receptor.1 Promotes skeletal...$40.00 – $160.00 Select options -
Approved Drugs
Amiodarone HCl | Pan-specific ion channel blocker
Amiodarone HCl (19774-82-4) is a nonselective ion channel blocker. Class III antiarrhythmic.1 Induces cytochrome c release and induces apoptosis.2 ...$45.00 Select options -
Calcium Signaling
Amlodipine | L-type Ca channel blocker
Amlodipine (88150-42-9) is an anti-hypertensive L-type calcium channel blocker, which also benefits the cardiovascular system by stimulating nitric...$30.00 – $55.00 Select options -
New Products
AP39 | Mitochondrial-targeted hydrogen sulfide donor
AP39 (1429173-57-8) is a mitochondrially targeted hydrogen sulfide donor. At lower concentrations (30 -100 nM), it acts as an electron donor and s...$110.00 – $425.00 Select options -
New Products
Apixaban | Factor Xa inhibitor
Apixaban (503612-47-3) is a potent and selective inhibitor of both free and prothrombin-bound factor Xa, Ki = 0.8 nM.1 Clinically useful antithromb...$50.00 – $185.00 Select options -
Cardiovascular
Argatroban | Thrombin inhibitor
Argatroban (74863-84-6) is a potent and selective inhibitor of thrombin (Ki = 19 nM).1 Prevents platelet-rich arterial thrombosis in a rabbit model...$56.00 – $224.00 Select options -
Cardiovascular
AS-8351 | KDM5B histone demethylase inhibitor
AS-8351 (796-42-9) has been used in a cocktail of nine small molecules used to efficiently induce cardiac reprogramming of human fibroblasts.1 It i...$50.00 – $200.00 Select options
