Atherosclerosis
Showing 1–12 of 17 results
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New Products
1G244 | DPP8/9 inhibitor
1G244 (847928-32-9) is a potent and selective inhibitor of the prolyl dipeptidases DPP8 (IC50 = 14 nM) and DPP9 (IC50 = 53 nM).1,2 It does not inh...$70.00 – $270.00 Select options -
Atherosclerosis
5alpha,6alpha-Epoxycholesterol | LXR ligand
5α,6α-Epoxycholesterol (1250-95-9) is a naturally occurring metabolite of cholesterol. It is a major oxysterol found in processed food1 and has be...$25.00 – $85.00 Select options -
Atherosclerosis
Atglistatin | ATGL inhibitor
Atglistatin (1469924-27-3) is the first small molecule inhibitor of adipose triglyceride lipase (ATGL) – IC50 = 700 nM.1 It exhibits high selectiv...$60.00 – $225.00 Select options -
New Products
Belnacasan | ICE/caspase-1 inhibitor
Belnacasan (273404-37-8) is a prodrug of VRT-043198, a potent (Ki = 0.8 nM ICE/caspase-1; <0.6nM caspase-4) and selective inhibitor of interleuk...$45.00 – $160.00 Select options -
New Products
Bempedoic acid | ATP citrate lyase inhibitor
Bempedoic acid (738606-46-7) is an inhibitor of ATP citrate lyase (ACL) and activator of AMPK used in the treatment of hypercholesterolemia.1,2 In ...$45.00 – $125.00 Select options -
Atherosclerosis
BMS-309403 | FABP4 inhibitor
BMS-309403 (300657-03-8) is a potent (Ki <2 nM FABP4, Ki = 250 nM FABP3, Ki = 350 nM FABP5) and selective inhibitor of the fatty-acid-binding pr...$60.00 – $225.00 Select options -
New Products
DT-109 | Induces glutathione biosynthesis
DT-109 (14857-82-0) is glycine-containing peptide which has been demonstrated to ameliorate nonalcoholic fatty liver disease (NAFLD). It improved b...$35.00 – $85.00 Select options -
Approved Drugs
Ezetimibe | Cholesterol absorption inhibitor
Ezetimibe (163222-33-1) inhibits cholesterol absorption in the intestine by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) pr...$45.00 – $140.00 Select options -
Approved Drugs
Fluvastatin Na | HMG CoA reductase inhibitor
Fluvastatin Na (CAS 93957-55-2) is a potent inhibitor of HMG-CoA reductase, IC50=40-100 nM.1 Clinically useful, orally active antihypercholesterol...$40.00 – $130.00 Select options -
Approved Drugs
Isradipine | L-type Ca channel blocker
Isradipine (75695-93-1) is an L-type calcium channel blocker. Displays antiatherosclerotic effects and improves endothelium-mediated nitric oxide-d...$64.00 – $256.00 Select options -
Atherosclerosis
Leonurine | Neuroinflammation inhibitor
Leonurine (CAS 24697-74-3) inhibits microglial overactivation and attenuates Aβ(1-40)-induced cognitive impairments in rats via JNK and NF-κB pathw...$48.00 – $180.00 Select options -
Approved Drugs
Lovastatin | HMG-CoA reductase inhibitor
Lovastatin (75330-75-5) Blocks cholesterol and isoprenoid biosynthesis via inhibition of HMG-CoA reductase (Ki=1nM for acid form).1,2 Induces apopt...$50.00 – $165.00 Select options
