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  • Citalopram HBr | Serotonin uptake inhibitor
    Citalopram (59729-32-7) is a potent and selective serotonin uptake inhibitor (SSRI) Ki=5.4 nM. Has no effect on norepinephrine or dopamine uptake.1 Displays cardioprotective effects in part by reducing expression of...

  • Focus Biomolecules cell signaling reagent supplier, structure of EPA free acid | omega-3 fatty acid | CAS 10417-94-4
    EPA free acid (10417-94-4) dietary enrichment may have anti-inflammatory effects by inhibiting the 5-lipoxygenase pathway and LTB4-mediated neutrophil functions.1 Displays various cardiovascular protective properties.2...

  • Focus Biomolecules cell signaling supplier, chemical structure of Leonurine | Neuroinflammation inhibitor | CAS 24697-74-3
    Leonurine (CAS 24697-74-3) inhibits microglial overactivation and attenuates Aβ(1-40)-induced cognitive impairments in rats via JNK and NF-κB pathways.1 Inhibits the formation of advanced glycation end products.2...

  • Focus Biomolecules supplier, chemical structure of Mitoquinone | Mitochondria-targeted antioxidant | CAS 444890-40-9
    Mitoquinone (444890-40-9) is a mitochondria-targeted antioxidant. Displays cardio- and neuroprotective effects.1 Displays beneficial effects in mouse models of Alzheimer's disease.2 Mitoquinone protects pancreatic...

  • Focus Biomolecules cell signaling reagent supplier, structure of Necrostatin-1 | Inhibits necroptosis | CAS 4311-88-0
    Necrostatin-1 (4311-88-0) is an inhibitor of necroptosis (non-apoptotic cell death pathway; EC50 = 494 nM).1 It is an ATP-competitive death domain receptor-associated adaptor kinase (RIP1) inhibitor (EC50 = 182 nM).2...

  • Focus Biomolecules cell signaling reagent supplier, structure of U-74389G | Free radical scavenger | CAS 153190-29-5
    U-74389G (153190-29-5) is an antioxidant and Inhibits iron-mediated lipid peroxidation.1 It has also been shown to reduce free radical-mediated injury after ischemia and reperfusion.2,3 References/Citations1) Braughler et...

  • Focus Biomolecules supplier, chemical structure Visnagin | Protects against doxorubicin-induced cardiomyopathy | CAS 82-57-5
    Visnagin (82-57-5) is a natural product isolated from the plant Ammi visnaga.  It displays protective effects against doxorubicin-induced cardiomyopathy via inhibition of mitochondrial malate dehydrogenase resulting in...

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