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Heart Failure

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  • Focus Biomolecules cell signaling reagent supplier, chemical structure of Disopyramide | Antiarrhythmic | CAS 3737-09-5
    $35.00
    Disopyramide (3737-09-5) is a clinically useful sodium channel blocker used as an antiarrhythmic for treatment of ventricular tachycardia1 and hypertrophic cardiomyopathy2.  It decreases the rate of diastolic...

  • Ivabradine HCl | Heart failure / unstable angina drug
    $49.00
    Ivabradine (148849-67-6) is a clinically useful heart failure and chronic unstable angina medication.1 It lowers heart rate via inhibition of hyperpolarization-activated cyclic nucleotide-gated channels (HCN) expressed in...

  • Focus Biomolecules supplier, structure of Nicardipine HCl | L-type Ca channel blocker / MDR inhibitor | CAS 54527-84-3
    $30.00
    Nicardipine (54527-84-3) is a clinically useful L-type calcium blocker. Inhibitor of MDR.2 References/Citations1) Merck 14 6495 2) Hulubei et al. (2012), 4-Isoxazolyl-1,4-dihydropyridines exhibit binding at the...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure Pyr3 | TRPC3 Channel blocker | CAS 1160514-60-2
    $111.00
    Pyr3 (1160514-60-2) is a selective antagonist of the TRP canonical 3 channel (TRPC3)1 which can function as a receptor-operated channel2. A useful tool for dissecting GPCR-downstream signaling mechanisms3. Pyr3 may be...

  • Focus Biomolecules cell signaling reagent supplier, structure of Ro 13-6438 | Quazinone | PDE3 inhibitor | CAS 70018-51-8
    $75.00
    Ro 13-6438 (70018-51-8) is a selective inhibitor of phosphodiesterase III (PDE III, IC50 = 0.6 μM). References/Citations1) Eigenmann et al. (1984) Cardiovascular profile of Ro 13-6438, a novel positive inotropic agent...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of Teprenone | HSP70 inducer | CAS 6809-52-5
    $50.00
    Teprenone (6809-52-5) induces expression of HSP70 after various types of stimuli.1,2 Protects against visceral adipocity and insulin resistance in high fat fed mice.3 Teprenone displays protective effects via enhanced...