Heart Failure
Showing all 10 results
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New Products
AZD5904 | Myeloperoxidase inhibitor
AZD5904 (618913-30-7) is a mechanism-based inactivator of myeloperoxidase (IC50 = 200 nM), reacting with hydrogen peroxide in neutrophils to inacti...$80.00 – $280.00 Select options -
New Products
BI 749327 | Selective TRPC6 blocker
BI 749327 (2361241-23-6) is a potent (IC50 = 13 nM mouse TRPC6, 19 nM human TRPC6) and selective (85-fold over TRPC3, 42-fold over TRC7) orally ava...$80.00 – $300.00 Select options -
Approved Drugs
Disopyramide | Antiarrhythmic
Disopyramide (3737-09-5) is a clinically useful sodium channel blocker used as an antiarrhythmic for treatment of ventricular tachycardia1 and hype...$35.00 – $95.00 Select options -
New Products
Honokiol | SIRT3 activator
Honokiol (35354-74-6) is a natural product that acts as a SIRT3 activator. It increases mitochondrial oxygen consumption and reduces ROS production...$55.00 – $220.00 Select options -
Approved Drugs
Ivabradine HCl | Heart failure / unstable angina drug
Ivabradine (148849-67-6) is a clinically useful heart failure and chronic unstable angina medication.1 It lowers heart rate via inhibition of hyper...$60.00 – $220.00 Select options -
New Products
Metolazone | UPR activator and longevity inducer
Metolazone (17560-51-9) activates mitochondrial unfolded protein response (UPRMT) and -increases C. elegans lifespan.4 Clinically useful diuretic t...$50.00 – $200.00 Select options -
Approved Drugs
Nicardipine HCl | L-type Ca channel blocker / MDR inhibitor
Nicardipine (54527-84-3) is a clinically useful L-type calcium blocker. Inhibitor of MDR.2 References/Citations: 1) Merck 14 6495 2) Hulubei...$30.00 – $50.00 Select options -
Cardiovascular
Pyr3 | TRPC3 Channel blocker
Pyr3 (1160514-60-2) is a selective blocker of the TRP canonical 3 channel (TRPC3)1 which can function as a receptor-operated channel2. A useful too...$90.00 – $310.00 Select options -
Cardiovascular
Ro 13-6438 | PDE3 inhibitor
Ro 13-6438 (70018-51-8) is a selective inhibitor of phosphodiesterase III (PDE III, IC50 = 0.6 μM). References/Citations: 1) Eigenmann et al....$75.00 – $300.00 Select options -
Approved Drugs
Teprenone | HSP70 inducer
Teprenone (6809-52-5) induces expression of HSP70 after various types of stimuli.1,2 Protects against visceral adipocity and insulin resistance in ...$50.00 – $130.00 Select options
