Hypertension
Showing 1–12 of 24 results
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Calcium Signaling
Amlodipine | L-type Ca channel blocker
Amlodipine (88150-42-9) is an anti-hypertensive L-type calcium channel blocker, which also benefits the cardiovascular system by stimulating nitric...$30.00 – $55.00 Select options -
Cardiovascular
Benzamil HCl | Sodium channel/transport blocker
Benzamil (161804-21-2) is a more potent (Ki = 10 nM vs 182 nM1, IC50 = 9 µM2) version of the epithelial sodium channel blocker Amiloride. It is als...$50.00 – $175.00 Select options -
ACE
Captopril | Angiotensin-converting enzyme inhibitor
Captopril (62571-86-2) is an angiotensin-converting enzyme (ACE) inhibitor (IC50 = 0.022 μM).1 Also inhibits the bifunctional Zn2+-containing leuko...$30.00 – $80.00 Select options -
Approved Drugs
Diazoxide | K-ATP channel activator
Diazoxide (364-98-7) activates ATP-dependent K+ channels1 via inducing translocation of PKC-epsilon from the cytosol to the mitochondria2. Hypergly...$50.00 – $150.00 Select options -
Approved Drugs
Diltiazem | Calcium channel blocker
Diltiazem HCl (33286-22-5) is a non-dihydropyridine-type blocker of L-type Ca2+ channels.1,2 Reduces Ca2+ oscillations in subcellular compartments ...$50.00 – $140.00 Select options -
Approved Drugs
Felodipine | L-type Ca channel blocker
Felodipine (72509-76-3) is a potent L-type Ca2+ channel blocker that is selective over N-, R-, P/Q- and T-type channels.1,2 It displays high vascul...$50.00 – $120.00 Select options -
New Products
GYY4137 | Hydrogen sulfide donor
GYY4137 (106740-09-4) is a water soluble hydrogen sulfide slow-releasing molecule.1 Rate of release at pH 7.4 and 37°C was 4.17 ± 0.5 nmol/25 min. ...$45.00 – $165.00 Select options -
Approved Drugs
Isradipine | L-type Ca channel blocker
Isradipine (75695-93-1) is an L-type calcium channel blocker. Displays antiatherosclerotic effects and improves endothelium-mediated nitric oxide-d...$64.00 – $256.00 Select options -
New Products
LMK235 | Selective HDAC4/5 inhibitor
LMK235 (1418033-25-6) is a potent and selective inhibitor of HDAC4 (IC50 = 11.9 nM) and HDAC5 (IC50 = 4.2 nM).1 Cytotoxic against human ovarian can...$60.00 – $225.00 Select options -
Approved Drugs
Losartan potassium | Angiotensin AT1 antagonist
Losartan potassium (124750-99-8) is a non-peptide angiotensin II receptor antagonist.1,2 Clinically useful antihypertensive agent.3 Inhibits collag...$40.00 – $160.00 Select options -
Antivirals
Manidipine dihydrochloride | Calcium channel blocker
Manidipine (89226-75-5) is a clinically useful antihypertensive.1,2 It is an inhibitor of L- and T-type calcium channels with high selectivity for ...$30.00 – $60.00 Select options -
Approved Drugs
Minoxidil | KATP channel opener
Minoxidil (38304-91-5) is a direct antihypertensive peripheral vasodilator acting via activation of KATP channels leading to relaxation of smooth m...$50.00 – $200.00 Select options
