Stem Cells
Showing all 9 results
-
Cardiovascular
1-EBIO | K+ channel activator; Promotes cardiomyocyte differentiation
1-EBIO (10045-45-1) is a direct activator of small-conductance Ca2+-activated K+ channels (SK) which dose-dependently relaxes rat mesenteric vessel...$40.00 – $148.00 Select options -
Cardiovascular
6BIO | GSK-3 inhibitor
6BIO (667463-62-9) is a potent and selective inhibitor of glycogen synthase kinase-3 (GSK-3) IC50=5 nM.1 The first pharmacological agent shown to m...$65.00 – $260.00 Select options -
Cardiovascular
AS-8351 | KDM5B histone demethylase inhibitor
AS-8351 (796-42-9) has been used in a cocktail of nine small molecules used to efficiently induce cardiac reprogramming of human fibroblasts.1 It i...$50.00 – $200.00 Select options -
Cardiovascular
IWP-2 | Porcn inhibitor: Wnt/Beta-catenin pathway inhibitor
IWP-2 (686770-61-6) is an inhibitor of Wnt secretion and processing. It blocks Wnt-dependent signaling (IC50= 27 nM) by inhibition of the O-acyltra...$55.00 – $175.00 Select options -
Cardiovascular
KY-02111 | Wnt pathway inhibitor
KY-02111 (1118807-13-8) promotes cardiac differentiation of human pluripotent stem cells. Inhibits Wnt signaling in a manner that appears to be dis...$55.00 – $220.00 Select options -
New Products
PTC-209 | BMI-1 inhibitor
PTC-209 (315704-66-6) is an inhibitor of BMI-1 (IC50 = 500 nM), part of the polycomb repressive complex 1 (PRC1).1 It inhibited endogenous BMI-1 e...$65.00 – $240.00 Select options -
Cardiovascular
SHZ-1 | Stem Cell – Myocardial differentiation
SHZ-1 (326886-05-9) triggers cardiac mRNA and protein expression in a variety of embryonic and adult stem/progenitor cells including human mobilize...$65.00 – $260.00 Select options -
Cancer
XAV-939 | Tankyrase inhibitor/Cardiomyogenesis inducer
XAV-939 (284028-89-3) is a tankyrase inhibitor (IC50=11 and 4 nM for TNKS1 and 2 respectively). Antagonizes wnt signaling via stimulation of β-cat...$50.00 – $150.00 Select options -
Angiogenesis
Zebularine | DNA methylation inhibitor
Zebularine (3690-10-6) is an orally active DNA methyltransferase inhibitor. Inhibits tumor cell proliferation (IC50 = 120 μM) and re-activates sile...$60.00 – $240.00 Select options
