my account
Login
  Loading... Please wait...

Aurora Kinase

Sort by
  • Focus Biomolecules cell signaling reagent supplier, chemical structure of Alisertib | Aurora A inhibitor | CAS 1028486-01-2
    $60.00
    Alisertib (MLN8237, 1028486-01-2) is a highly selective and potent (IC50 = 1 nM) cell permeable inhibitor of Aurora A with off-target binding at GABAA (IC50 = 490 nM).1 It disrupts the Aurora A-Myc complex leading to Myc...

  • AZD1152-HQPA | Aurora B kinase inhibitor
    $50.00
    AZD1152-HQPA (722544-51-6) is a potent and highly selective inhibitor of Aurora B.1 Aurora B Ki = 0.36 nM; Aurora A Ki = 1,369 nM.2 It inhibits the growth of tumors in multiple cancer models.3-6 Excessive ROS generation7 and...

  • SNS-314 mesylate | Aurora kinase inhibitor
    $70.00
    SNS-314 mesylate (1146618-41-8) is a potent and selective pan-Aurora kinase inhibitor (IC50’s: Aurora A = 9 nM, Aurora B = 31 nM, Aurora C = 3 nM.1,2 It was able to inhibit proliferation in a wide panel of human cancer...

  • Focus Biomolecules supplier, chemical structure of Tozasertib | Aurora kinase inhibitor | CAS 639089-54-6
    $50.00
    Tozasertib (639089-54-6) is an inhibitor of Aurora kinases.1 Blocks cell cycle progressing, inhibits proliferation, and induces apoptosis in a wide range of cancer cell lines (IC50 <10 μM for clear cell renal...

  • Focus Biomolecules cell signaling reagent supplier, structure of ZM-447439 | Aurora B kinase inhibitor | CAS 331771-20-1
    $48.00
    ZM-447439 (331771-20-1) is a selective ATP-competitive inhibitor of Aurora kinase B1 (IC50 = 50 nM, Aur A IC50 = 1 μM, Aur C IC50 = 250 nM at physiological ATP concentrations2, Ref.1 lists Aur A IC50 = 110nM and Aur B...