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Cell Death

Cell death can be divided in two major categories. Necrosis results from cellular injury caused by external factors such as trauma or infection. Programmed cell death is a regulated process that is mediated by various intracellular programs. Types of programmed cell death include apoptosis, anoikis, necroptosis, ferroptosis, pyroptosis, and parthanatos. These types of programmed cell death other than apoptosis have also been termed stress-induced cell death (SCID).

View All Cell Death Reagents

Apoptosis

  • Z-VAD-FMK

    Cell permeable, irreversible, pan-caspase inhibitor

  • Staurosporine

    Staurosporine is a pan-kinase inhibitor widely used to induce apoptosis

  • C2-Ceramide

    Cell permeable ceramide analog that induces apoptosis in a wide variety of cell types

  • Obatoclax

    Obatoclax is a pan-inhibitor of Bcl-2-family proteins

View All Apoptosis Reagents

Necroptosis

  • 7-Cl-O-Nec1

    Selective inhibitor of RIP1

  • GSK872

    GSK872 is a potent and selective inhibitor of RIP3 that blocks necroptosis and necrosis

  • RIPA-56

    Potent and selective inhibitor of RIP1

  • Necrosulfonamide

    MLKL inhibitor that blocks necroptosis downstream of RIP3

View All Necroptosis Reagents

Ferroptosis

  • Erastin

    Induces ferroptosis via inhibition of the cystine-glutamate antiporter, system Xc-

  • Ferrostatin-1

    Ferrostatin-1 is a potent inhibitor of ferroptosis

View All Ferroptosis Reagents

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

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