Cell Death
Showing 1–12 of 171 results
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New Products
1G244 | DPP8/9 inhibitor
1G244 (847928-32-9) is a potent and selective inhibitor of the prolyl dipeptidases DPP8 (IC50 = 14 nM) and DPP9 (IC50 = 53 nM).1,2 It does not inh...$70.00 – $270.00 Select options -
Cell Death
24(S)-Hydroxycholesterol | Endogenous cholesterol metabolite
24(S)-Hydroxycholesterol (474-73-7) is an important cholesterol metabolite (cholesterol 24-hydroxylase) found in the brain.1 It is an endogenous ag...$60.00 – $280.00 Select options -
ADP-ribosylation
3-Aminobenzamide | PARP inhibitor
3-Aminobenzamide (3544-24-9) inhibits endogenous poly-ADP-ribosyltransferases.1 Inhibits nitric oxide-induced apoptosis but not differentiation in ...$50.00 Select options -
Apoptosis
5-Fluorouridine | Proapoptotic antiproliferative agent
5-Fluorouridine (316-46-1) is an inhibitor of ribozyme self-cleavage in mammalian cells.1 Induces apoptosis in HCT-116 colorectal carcinoma cells ...$60.00 – $130.00 Select options -
Apoptosis
7-Aminoactinomycin D | Fluorescent DNA Probe
7-Aminoactinomycin D (7240-37-1) is a fluorescent, intercalating DNA-binding agent useful for identifying apoptotic cells by flow cytometry. 1,2 Ca...$96.00 – $380.00 Select options -
Cell Death
7-Cl-O-Nec1 | RIP1 inhibitor
7-Cl-O-Nec1 (852391-15-2) is a necrostatin-1 (Cat.# 10-1162) analogue with superior potency (IC50 = 206nM vs 494nM), selectivity and metabolic stab...$60.00 – $205.00 Select options -
Apoptosis
ABT-263 | Bcl-2 family inhibitor; Senolytic agent
ABT-263 (923564-51-6) is a potent and selective Bcl-2 family inhibitor / BH3 domain mimetic which binds to Bcl-2, Bcl-xL and Bcl-w (Ki<1 nM). A ...$60.00 – $200.00 Select options -
Aminopeptidases
Actinonin | Leucyl aminopeptidase inhibitor
Actinonin (13434-13-4) is a potent hydroxamic acid inhibitor of aminopeptidases which displays analgesic effects by inhibiting enkephalin-degrading...$35.00 – $95.00 Select options -
Apoptosis
Adapalene | Retinoid RARbeta, gamma agonist
Adapalene (106685-40-9) is a stable analog of retinoic acid that acts as a selective agonist for RARβ and RARγ. Adapalene also inhibits proliferati...$30.00 – $50.00 Select options -
Apoptosis
AG-1296 | PDGFR kinase inhibitor
AG-1296 (146535-11-7) is a potent inhibitor of PDGF receptor kinase (IC50 = 1 μM), c-kit and FGF kinase. Induces apoptosis in H526, small-cell lung...$60.00 – $260.00 Select options -
ALK
Alectinib | Potent and selective ALK inhibitor
Alectinib (1256580-46-7) is a potent (IC50 = 1.9 nM) and highly selective ALK inhibitor.1 It blocked phosphorylation of both native ALK and the L11...$60.00 – $205.00 Select options -
Calpains
ALLN | Calpain inhibitor
ALLN (110044-82-1) is a cell-permeable, peptide aldehyde inhibitor of calpain I (Ki=190 nM), calpain II (Ki=150 nM), cathepsin L (Ki=0.5 nM) and ot...$50.00 – $188.00 Select options
