Apoptosis
Showing 1–12 of 141 results
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ADP-ribosylation
3-Aminobenzamide | PARP inhibitor
3-Aminobenzamide (3544-24-9) inhibits endogenous poly-ADP-ribosyltransferases.1 Inhibits nitric oxide-induced apoptosis but not differentiation in ...$50.00 Select options -
Apoptosis
5-Fluorouridine | Proapoptotic antiproliferative agent
5-Fluorouridine (316-46-1) is an inhibitor of ribozyme self-cleavage in mammalian cells.1 Induces apoptosis in HCT-116 colorectal carcinoma cells ...$60.00 – $130.00 Select options -
Apoptosis
7-Aminoactinomycin D | Fluorescent DNA Probe
7-Aminoactinomycin D (7240-37-1) is a fluorescent, intercalating DNA-binding agent useful for identifying apoptotic cells by flow cytometry. 1,2 Ca...$96.00 – $380.00 Select options -
Apoptosis
ABT-263 | Bcl-2 family inhibitor; Senolytic agent
ABT-263 (923564-51-6) is a potent and selective Bcl-2 family inhibitor / BH3 domain mimetic which binds to Bcl-2, Bcl-xL and Bcl-w (Ki<1 nM). A ...$60.00 – $200.00 Select options -
Aminopeptidases
Actinonin | Leucyl aminopeptidase inhibitor
Actinonin (13434-13-4) is a potent hydroxamic acid inhibitor of aminopeptidases which displays analgesic effects by inhibiting enkephalin-degrading...$35.00 – $95.00 Select options -
Apoptosis
Adapalene | Retinoid RARbeta, gamma agonist
Adapalene (106685-40-9) is a stable analog of retinoic acid that acts as a selective agonist for RARβ and RARγ. Adapalene also inhibits proliferati...$30.00 – $50.00 Select options -
Apoptosis
AG-1296 | PDGFR kinase inhibitor
AG-1296 (146535-11-7) is a potent inhibitor of PDGF receptor kinase (IC50 = 1 μM), c-kit and FGF kinase. Induces apoptosis in H526, small-cell lung...$60.00 – $260.00 Select options -
ALK
Alectinib | Potent and selective ALK inhibitor
Alectinib (1256580-46-7) is a potent (IC50 = 1.9 nM) and highly selective ALK inhibitor.1 It blocked phosphorylation of both native ALK and the L11...$60.00 – $205.00 Select options -
Angiogenesis
Alsterpaullone | GSK-3ß inhibitor
Alsterpaullone (237430-03-4) is a potent and selective inhibitor of GSK-3β and CDK5/p25. Potent inhibitor of CDK1/cyclin B (IC50 = 35 nM).1 Alsterp...$56.00 – $224.00 Select options -
Apoptosis
Amifostine | Cellular protectant
Amifostine (20537-88-6) is a broad spectrum radio- and chemoprotective agent.1 Prevents chemotherapy-induced apoptosis, upregulates HIF-1α and rest...$56.00 – $224.00 Select options -
Antivirals
Andrographolide | Induces mitochondrial-mediated apoptosis
Andrographolide (5508-58-7) is the major bioactive component of the medicinal plant Andrographis paniculate. Demonstrates anti-inflammatory anti-ap...$34.00 – $136.00 Select options -
Apoptosis
Ansamitocin P3 | Microtubule depolymerizer
Ansamitocin P3 (66547-09-9) is a fungal metabolite from Actinosynnema pretiosum which binds to the phomopsin A/rhizoxin site on tubulin.1,2 Ansamit...$50.00 – $120.00 Select options
