Ferroptosis
Showing all 11 results
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New Products
Altretamine | Ferroptosis inducer
Altretamine (645-05-6) induces ferroptosis by inhibiting glutathione peroxidase 4 (GPX4) which causes accumulation of lipid hydroperoxides.1 Ferrop...$35.00 – $100.00 Select options -
New Products
Deferasirox | Iron Chelator
Deferasirox (201530-41-8) is a clinically useful iron chelator used in long term care of ß-thalassemia and other heavily transfused hematological p...$50.00 – $135.00 Select options -
Cell Death
Erastin | Ferroptosis inducer
Erastin (571203-78-6) is a ferroptosis inducer.1 Inhibits the cystine-glutamate antiporter, system Xc- leading to activation of an ER stress respon...$65.00 – $260.00 Select options -
Antioxidants
Ferrostatin-1 | Ferroptosis inhibitor
Ferrostatin-1 (347174-05-4) inhibits ferroptosis (EC50=60 nM), an iron-dependent form of nonapoptotic cell death.1 Potent inhibitor of ferroptosis ...$45.00 – $160.00 Select options -
New Products
FIN56 | Ferroptosis inducer
FIN56 (1083162-61-1) is a novel inducer of ferroptosis acting via degradation of GPX4 and activation of squalene synthase (leading to CoQ10 depleti...$65.00 – $235.00 Select options -
New Products
Liproxstatin-1 | Ferroptosis inhibitor
Liproxstatin-1 (950455-15-9) is an inhibitor of ferroptosis (IC50 = 22 nM).1 It was able to mitigate tissue injury in a mouse model of hepatic isch...$65.00 – $250.00 Select options -
Cancer
ML210 | GPX4 inhibitor / Ferroptosis inducer
ML210 (CAS 1360705-96-9) is selectively synthetic lethal to HRAS expressing cells compared to isogenic non-HRAS cells (IC50 = 7.1 nM for BJeLR (exp...$75.00 – $275.00 Select options -
New Products
Nocardamine | Iron chelator/Ferroptosis inhibitor
Nocardamine (26605-16-3) is a bacterially produced siderophore1 which can act as an intracellular ion chelator2. A cyclic analog of the ferroptosi...$125.00 Select options -
New Products
RSL3 | GPX4 inhibitor/Ferroptosis inducer
RSL3 (1219810-16-8) Inhibits glutathione peroxidase (GPX4) inducing ferroptosis.1,2 Effectively induces ferroptosis in glioblastoma cells.3 Evero...$85.00 – $250.00 Select options -
Autophagy
Salinomycin Na | Cancer stem cell inhibitor
Salinomycin Na (55721-31-8) is a polyether ionophore with antibiotic and anti-cancer properties. It induces cell death in some types of cancer cell...$30.00 – $80.00 Select options -
New Products
SRS16-86 | Ferroptosis inhibitor
SRS16-86 (1793052-96-6) is a third generation ferrostatin derivative with greater metabolic and plasma stability for in vivo studies. It protected ...$69.00 – $219.00 Select options
