Cellular Metabolism
Showing 1–12 of 113 results
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New Products
2-AAPA | Glutathione/thioredoxin reductase inhibitor
2-AAPA (1133387-90-2) inhibits glutathione reductase and thioredoxin reductase,IC50s=6.7 and 8.7 µM respectively, and impairs mitochondrial functio...$60.00 – $240.00 Select options -
Cancer
2-Deoxy-D-Glucose | Biologically active glucose analog
2-Deoxy-D-glucose (154-17-6) is a synthetic glucose analog with extensive biological effects. It is commonly thought of as an inhibitor of glycolys...$40.00 – $160.00 Select options -
Cellular Metabolism
2-NBD-Glucose | Glucose uptake probe
2-NBD-Glucose (186689-07-6) is a fluorescent glucose uptake probe. May be used to monitor glucose uptake in live cells and as a cell viability indi...$40.00 – $160.00 Select options -
Cancer
3PO | 6-Phosphofructo-2-kinase (PFKFB3) inhibitor
3PO (18550-98-6) is an inhibitor of the metabolic enzyme 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3). PFKFB3 is constitutively...$45.00 – $170.00 Select options -
Cancer
680C91 | Tryptophan 2,3-dioxygenase inhibitor
680C91 (163239-22-3) is a potent and selective inhibitor of tryptophan 2,3-dioxygenase (TDO) Ki=42 nM).1,2 Displays no activity against indoleamine...$68.00 – $272.00 Select options -
Cellular Metabolism
A77 1726 | DHODH inhibitor
A77 1726 (108605-62-5) is a pyrimidine biosynthesis inhibitor and immunomodulator.1 Inhibits the mitochondrial dihydroorotate dehydrogenase (DHODH)...$45.00 – $150.00 Select options -
New Products
ABX-1431 | MAGL inhibitor
ABX-1431 (1446817-84-0) is a potent (IC50 = 14 nM in vitro, 2.2 nM in human PC3 cells) and very selective (>100-fold over hABHD6, >200-fold o...$60.00 – $235.00 Select options -
Bioactive Lipids
Acetyl-Coenzyme A 3Li | Acetylation and fatty acid biosynthesis cofactor
Acetyl-CoA (75520-41-1) is an essential cofactor for cellular metabolism, being an ‘activated acetate’ that shuttles its moieties back and forth du...$65.00 – $260.00 Select options -
Cancer
AGI-5198 | R132 mutant isocitrate dehydrogenase inhibitor
AGI-5198 (135526-35-0) is a potent (IC50 = 70 nM) inhibitor of mutant isocitrate dehydrogenase 1(IDH1).1 It is selective for the R132H-IDH1 mutant...$40.00 – $95.00 Select options -
Cancer
Arecoline HBr | ACAT1 inhibitor
Arecoline (CAS 300-8-3) is a covalent inhibitor of ACAT1 which binds to and disrupts only ACAT1 tetramers (IC50=11.1 μM). ACAT2 and DLAT are not in...$30.00 – $60.00 Select options -
New Products
AS-1949490 | SHIP2 inhibitor
AS-1949490 (1203680-76-5) is a potent and selective inhibitor of the intracellular phosphatase SHIP2 (SH2 domain-containing inositol 5'-phosphatas...$62.00 – $248.00 Select options -
Atherosclerosis
Atglistatin | ATGL inhibitor
Atglistatin (1469924-27-3) is the first small molecule inhibitor of adipose triglyceride lipase (ATGL) – IC50 = 700 nM.1 It exhibits high selectiv...$60.00 – $225.00 Select options
