Bithionol | Glutamate dehydrogenase inhibitor

CAS:
97-18-7
Catalog Number:
10-4567
Activity:
Glutamate dehydrogenase inhibitor
Chemical Name:
Bis(2-hydroxy-3,5-dichlorophenyl)sulfide
Molecular Weight:
356.05
Molecular Formula:
C12H6Cl4O2S
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
98%
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
100 mg$20.00
500 mg$50.00

Bithionol (97-18-7) is an antihelmintic drug with bacteriostatic and fungicidal properties. Bithionol has also been found to be an inhibitor of glutamate dehydrogenase1,2 (IC50 = 4.8 μM bovine GDH1).

References/Citations:

1) Li et al. (2009), Novel inhibitors complexed with glutamate dehydrogenase: allosteric regulation by control of protein dynamics; J. Biol. Chem., 284 22988
2) Zocher et al. (2012), Biochemical and structural characterization of Plasmodium falciparum glutamate dehydrogenase 2; Mol. Biochem. Parasitol., 183 52

CAS:
97-18-7
Catalog Number:
10-4567
Activity:
Glutamate dehydrogenase inhibitor
Chemical Name:
Bis(2-hydroxy-3,5-dichlorophenyl)sulfide
Molecular Weight:
356.05
Molecular Formula:
C12H6Cl4O2S
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
98%
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee