Cellular Metabolism - Complex Carbohydrates

Castanospermine | Glucosidase inhibitor

$80.00

Castanospermine (79831-76-8) is a natural product, derived from Castanospermum austral. Potent inhibitor of α- and β-glucosidases.1 Exhibits antiviral properties.2 Inhibits HIV infectivity.3 Inhibits thyroglobulin...

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Conduritol B epoxide | Glycosidase inhibitor

$45.00

Conduritol B epoxide (6090-95-5) is a β-Glycosidase inhibitor.1,2 May be used for generation of the “Gaucher mouse”3 and the in vitro model of the Gaucher cell4. References/Citations 1) Datta and Radin...

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Deoxymannojirimycin HCl | Mannosidase inhibitor

$35.00

Potent and selective inhibitor of α-mannosidase I.1,2 Inhibits the conversion of high mannose to complex oligosaccharides.3 Attenuates tunicamycin-, thapsigargin- and Aβ1-42-induced ER stress dependent neuronal...

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Deoxynojirimycin | Glucosidase inhibitor

$50.00

Deoxynojirimycin (19130-96-2) inhibits α-glucosidase I and II1,2. Inhibits human immunodeficiency virus envelope glycoprotein-mediated membrane fusion at the CXCR4 binding step3. May be used to produce an affinity...

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Isofagomine tartrate | Glucocerebrosidase activator and chaperone

$100.00

Isofagomine tartrate (957230-65-8) is a competitive inhibitor of human lysosomal β-glucosidase, IC50 = 0.06 μM.1 Increases the activity of N370S mutant acid β-glucosidase (GlcCerase) in Gaucher fibroblasts.2...

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Kifunensine | Mannosidase inhibitor

$80.00

Historically isolated from Kitasato kifunensine.1 Inhibitor of class I α-mannosidases which inhibit glycoprotein processing. Inhibits human endoplasmic reticulum α-1,2-mannosidase I and Golgi Class I mannosidases...

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Miglitol | beta-glucosidase inhibitor / antidiabetic

$60.00

Miglitol (72432-03-2) is an α-glucosidase inhibitor which induces an enhanced and prolonged release of glucagon-like peptide-1, regulating appetite and stabilizing body weight in humans1. Miglitol displays...

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Miglustat HCl | Alpha-glucosidase inhibitor

$110.00

Miglustat HCl (210110-90-0) is an orally active ceramide-specific glycosyltransferase and α-glucosidase I and II inhibitor.1 Rescues trafficking-deficient F508del-CFTR in human airway epithelial cells via inhibition of...

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NGI-1 | Oligosaccharyltransferase (OST) inhibitor

$70.00

NGI-1 (790702-57-7) is a cell-permeable inhibitor of oligosaccharyltransferase (OST) – IC50 = 1.1 µM.1 It blocks cell-surface localization and signaling of the epidermal growth factor receptor (EGFR) glycoprotein...

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Swainsonine | Glycosidase inhibitor

$70.00

Swainsonine (72741-87-8) is a naturally occurring alkaloidal toxin found in locoweed. Inhibits the biosynthesis of complex glycoproteins by inhibition of Golgi mannosidase II (IC50 = 0.2 mM).1 Inhibits growth and potentiates...

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Thiamet G | O-GlcNAcase alpha 1 antagonist

$70.00

Thiamet G (1009816-48-1) is a potent, selective inhibitor of O-GlcNAcase (Ki = 21 nM for human O-GlcNAcase). Increases levels of O-GlcNAc-modified proteins in cellular assays and in vivo. Suppresses phosphorylation of tau...

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Tunicamycin | ER stress inducer

$74.00

Tunicamycin (11089-65-9) is a fermentation product from Streptomyces lysosuperificus. Provided as a mixture of tunicamycin A (C14), B (C15), C (C16) and D (C17) homologs varying in the number of carbon atoms in the...

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Complex Carbohydrates

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