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  • CHS-828 | NAMPT inhibitor
    CHS-828 (200484-11-3) is a potent and selective inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme in the biosynthesis of NAD, which may be used to deplete cells of NAD.1 Displays potent...

  • FK-866 HC; | 658084-64-1 (free base) | Structure | Supplier
    FK866 HCl (658084-64-1 base) is a nicotinamide phosphoribosyltransferase inhibitor (Ki=0.4 nM). Induces tumor cell apoptosis. FK-866 HCl extends lifespan of human cells. Cell permeable. References/Citations 1) Hasmann et...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of HQNO | NADH oxidase inhibitor | CAS 341-88-8
    HQNO (341-88-8) is a naturally occurring antagonist of dihydrostreptomycin. Potent inhibitor of the respiratory chain binding to the mitochondrial cytochrome b protein. HQNO inhibits NADH oxidase (NADH) and Na+-dependent...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of P7C3 | Neuroprotective agent | CAS 301353-96-8
    P7C3 exerts proneurogenic activity by protecting newborn neurons from apoptosis. Prolonged administration to aged rats impedes neuronal death and preserves cognitive capacity.1 Delays disease progression in G93A-SOD2 mutant...

  • STF-31 | NAMPT inhibitor
    STF-31 (724741-75-7) is an inhibitor of glucose transporter 1 (GLUT1; IC50 = 1 μM)1 and NAMPT3. Inhibition of glucose transporters to target It has been shown to kill renal cell carcinoma cells (the majority of which lack...

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