Cellular Metabolism - Polyamine - Focus Biomolecules

Difluoromethylornithine HCl | Inhibits polyamine biosynthesis

$30.00

Difluoromethylornithine HCl (96020-91-6) is a selective inhibitor of ornithine decarboxylase.1 Induces apoptosis in a variety of cells.2 Difluoromethylornithine HCl displays cancer chemopreventive activity...

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Mitoguazone 2HCl | Polyamine biosynthesis inhibitor / SAM decarboxylase inhibitor

$70.00

Mitoguazone (7059-23-6) is a potent and reversible inhibitor of S-adenosylmethionine decarboxylase (SAMD or AdoMetDC).1,2 SAMD is a component of the polyamine-biosynthetic pathway, thus inhibition may lead to changes in...

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PF-9366 | Methionine adenosyltransferase 2A inhibitor

$60.00

PF-9366 (72882-78-1) is an allosteric inhibitor (IC50 = 420 nM) of methionine adenosyltransferase 2A (Mat2A), the primary enzyme responsible for extrahepatic synthesis of S-adenosyl-L-methionine (SAM).1 It inhibited cellular...

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POB | Ornithine decarboxylase inhibitor

$70.00

POB is a transition state-based, cell permeable pro-drug inhibitor of ODC, a key enzyme involved in polyamine synthesis and a potential cancer drug target. Intracellularly, POB is phosphorylated by pyridoxal kinase and the...

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Polyamine