Cellular Stress
Autophagy DNA Damage ER Stress HSP HIF mTOR p53 Programmed cell death ROS Ubiquitin Proteasome UPR NF-kB Heat Shock Other
Showing 1–12 of 109 results
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Bone and Connective Tissue
1,4-DPCA | Prolyl hydroxylase inhibitor
1,4-DPCA (331830-20-7) is a potent inhibitor of prolyl 4-hydroxylase (IC50=2-4 μM)1. Inhibits collagen deposition via inhibition of collagen prolin...$60.00 – $220.00 Select options -
Angiogenesis
17-AAG | HSP90 inhibitor
17-AAG (75747-14-7) is a semi-synthetic analog of geldanamycin (Cat.# 10-1084) which is less toxic and more stable. 17-AAG selectively binds to and...$28.00 – $60.00 Select options -
Cellular Stress
17-AHA-Geldanamycin | Geldanamycin affinity chromatography ligand
17-AHA-geldanamycin is a semi-synthetic analog of geldanamycin containing a linker bearing a free NH2 functional group for conjugation. Selectively...$100.00 – $400.00 Select options -
Angiogenesis
17-DMAG | HSP90 inhibitor
17-DMAG (150270-08-9) is an analog of geldanamycin (Cat.# 10-1084) that displays superior pharmacological properties. 17-DMAG inhibits HSP90 and in...$50.00 – $125.00 Select options -
Cancer
17-GMP-APA-GA | Modified Geldanamycin
17-GMP-APA-GA is an analog of geldanamycin (Cat.# 10-1084) equipped with linker for coupling to proteins or antibodies for the preparation of immun...$185.00 Select options -
Cellular Stress
17-PAAG | Propargyl geldanamycin click reagent
17-PAAG is a semi-synthetic analog of geldanamycin which possesses an acetylenic side chain for coupling to other probes, fluorophores and bioactiv...$55.00 – $130.00 Select options -
Autophagy
3-Methyladenine | Autophagosome inhibitor
3-Methyladenine (5142-23-4) inhibits autophagy by blocking autophagosome formation via inhibition of type III phosphatidylinositol 3-kinases (PI-3K...$30.00 – $90.00 Select options -
Cellular Stress
4μ8C | IRE1 ribonuclease inhibitor
4μ8C (14003-96-4) is a selective inhibitor of IRE1α ribonuclease (RNase) activity (IC50 = 60 nM). Covalently binds to lysine 907 in the IRE1 endonu...$75.00 – $300.00 Select options -
Cancer
5-Fluorouracil | Inhibitor of thymidylate synthase
5-Fluorouracil (51-21-8) is a clinically useful anticancer agent that acts via irreversible inhibition of thymidylate synthase. The active metaboli...$20.00 – $40.00 Select options -
Cancer
8-Oxo-2′-deoxyguanosine | Marker for DNA damage
8-Oxo-2'-deoxyguanosine (88847-89-6) is a useful marker for DNA damage via a variety of oxidative processes1. It is a critical biomarker for oxidat...$38.00 – $160.00 Select options -
AMPK
AICAR | AMPK activator
Activates AMP-activated protein kinase (AMPK). Promotes ligand-independent activation of the insulin receptor.1 Promotes skeletal muscle autophagy ...$30.00 – $120.00 Select options -
Apoptosis
Amifostine | Cellular protectant
Amifostine (20537-88-6) is a broad sprectrun radio- and chemoprotective agent.1 Prevents chemotherapy-induced apoptosis, upregulates HIF-1α and res...$56.00 – $224.00 Select options
