HSP
Showing all 11 results
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Angiogenesis
17-AAG | HSP90 inhibitor
17-AAG (75747-14-7) is a semi-synthetic analog of geldanamycin (Cat.# 10-1084) which is less toxic and more stable. 17-AAG selectively binds to and...$32.00 – $80.00 Select options -
Angiogenesis
17-DMAG | HSP90 inhibitor
17-DMAG (150270-08-9) is an analog of geldanamycin (Cat.# 10-1084) that displays superior pharmacological properties. 17-DMAG inhibits HSP90 and in...$32.00 – $80.00 Select options -
Cancer
17-GMP-APA-GA | Modified Geldanamycin
17-GMP-APA-GA is an analog of geldanamycin (Cat.# 10-1084) equipped with linker for coupling to proteins or antibodies for the preparation of immun...$140.00 – $500.00 Select options -
Cardioprotection
BGP-15 | Cellular protectant
BGP-15 (66611-37-8) is a cellular protectant operating by several mechanisms. It is an insulin sensitizer1, HSP72 activator2, PARP inhibitor and RO...$90.00 – $360.00 Select options -
New Products
BIIB021 | HSP90 Inhibitor
BIIB021 is a potent HSP90 inhibitor (IC50 = 30 nM HER-2 degradation).1 It inhibited the proliferation of MCF7 and BT474 breast cancer cell lines (I...$50.00 – $175.00 Select options -
Apoptosis
Geldanamycin | HSP90 inhibitor
Geldanamycin (30562-34-6) inhibits HSP90 by binding to its ATP-binding domain (Kd=1.2 μM) and subsequently inhibits HSP90 client proteins. Geldanam...$50.00 – $100.00 Select options -
Cellular Stress
HPA | HDAC inhibitor
HPA (96017-59-3) is a histone deacetylase (HDAC) inhibitor, IC50=13 μM.1 More potent and robust than valproic acid at inducing histone hyperacetyla...$40.00 – $90.00 Select options -
New Products
KNK437 | HSP70 inhibitor
KNK437 (218924-25-5) Inhibits constitutive and inducible HSP70 expression in non-stressed1 and heat-stressed2 cancer cells. Blocks the geldanamycin...$60.00 – $180.00 Select options -
New Products
Luminespib | HSP90 inhibitor
Luminespib (747412-493) is a potent inhibitor (IC50 = 21 nM) of HSP90.1 It is active against various human tumor xenograft models acting via severa...$45.00 – $145.00 Select options -
Apoptosis
Pifithrin µ | Hsp70 inhibitor
Pifithrin μ (64984-31-2) selectively interacts with HSP70 and disrupts its association with co-chaperones and substrate proteins. Inhibits p53 bind...$45.00 – $170.00 Select options -
Approved Drugs
Zafirlukast | HSP70 inhibitor and leukotriene antagonist
Zafirlukast (107753-78-6) is a competitive and selective leukotriene receptor antagonist.1 Also inhibits calcium ionophore induced production of le...$28.00 – $55.00 Select options
