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  • Anacardic Acid | HAT inhibitor
    Anacardic acid (16611-84-0) is a natural product found in cashew nut oil. It is an inhibitor of the histone acetyltransferases p300 and PCAF (IC50’s = 8.5 and 5.0 µM respectively).1 Anacardic acid sensitizes...

  • Cardamonin | NFkB inhibitor
    Cardamonin (19309-14-9) inhibits NF-κB activation via inhibition of IκBα degradation and phosphorylation, IκB kinase activation and NF-κB nuclear translocation1,2. Cardamonin displays...

  • DMAPT | NFkB inhibitor
    DMAPT (870677-05-7) is a water soluble analog of the natural plant product parthenolide (Cat.# 10-2096) which suppresses in vivo tumor growth of two tobacco-associated neoplasms, lung and bladder cancer. It inhibits...

  • Helenalin | NFkB inhibitor
    Helenalin (6754-13-8) is a novel sesquiterpene lactone which inhibits NFκB1 and displays potent anti-inflammatory activity2. It suppresses essential immune functions of activated CD4+ T cells by multiple mechanisms3...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of Oxaprozin | NFkB inhibitor | CAS 21256-18-8
    Oxaprozin (21256-18-8) is a clinically useful non-steroidal anti-inflammatory drug.1 In addition to typical NSAID COX inhibition, oxaprozin may also exert anti-inflammatory effects via inhibition of the Akt/IKK/NF-κB...

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