Cholesterol
Showing 1–12 of 24 results
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Adipogenesis
20(S)-Hydroxycholesterol | Smoothened activator
20-(S)-Hydroxycholesterol (516-72-3) is an endogenous ligand for the LXR receptor.1 It has anti-adipogenic and pro-osteogenic effects in mesenchyma...$40.00 – $90.00 Select options -
Cell Death
24(S)-Hydroxycholesterol | Endogenous cholesterol metabolite
24S Hydroxycholesterol (474-73-7) is an important cholesterol metabolite (cholesterol 24-hydroxylase) found in the brain.1 It is an endogenous agon...$50.00 – $245.00 Select options -
Cholesterol
24(S),25-Epoxycholesterol | LXR agonist
24(S),25-Epoxycholesterol (77058-74-3) is a cholesterol metabolite that acts as an endogenous agonist for nuclear receptor LXR.1 Controls cellular ...$75.00 – $300.00 Select options -
Cholesterol
25-Hydroxycholesterol | Biologically active cholesterol metabolite
25 Hydroxycholesterol (2140-46-7) is a metabolite resulting from the action of cholesterol 25-hydroxylase on cholesterol. However, since cholestero...$30.00 – $105.00 Select options -
Alzheimers
27-Hydroxycholesterol | Cholesterol oxidation metabolite
27-Hydroxycholesterol (20380-11-4) is a metabolite resulting from the action of sterol 27-hydroxylase on cholesterol. Concentrations of 27-hydroxyc...$40.00 – $175.00 Select options -
Atherosclerosis
5alpha,6alpha-Epoxycholesterol | LXR ligand
5α,6α-Epoxycholesterol (1250-95-9) is a naturally occurring metabolite of cholesterol. It is a major oxysterol found in processed food1 and has be...$25.00 – $85.00 Select options -
Cholesterol
7alpha-Hydroxycholesterol | Bile acid precursor
7α-Hydroxycholesterol (566-26-7) is a metabolite resulting from the action of cholesterol 7α-hydroxylase on cholesterol. 7α-Hydroxycholesterol is t...$30.00 – $90.00 Select options -
Bioactive Lipids
AK-7 | SIRT2 inhibitor
AK-7 (420831-40-9) is a selective Sirt2 inhibitor (IC50=15.5 μM) which does not inhibit Sirt1 or Sirt3.1 It down regulates cholesterol biosynthesis...$50.00 – $185.00 Select options -
Approved Drugs
Ezetimibe | Cholesterol absorption inhibitor
Ezetimibe (163222-33-1) inhibits cholesterol absorption in the intestine by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) pr...$45.00 – $140.00 Select options -
Bioactive Lipids
Filipin III | Cholesterol probe
Filipin III (480-49-9) is a polyene macrolide antibiotic. It may be used in a double staining procedure for the detection of lipoproteins.1 Binds s...$120.00 – $480.00 Select options -
Approved Drugs
Fluvastatin Na | HMG CoA reductase inhibitor
Fluvastatin Na (CAS 93957-55-2) is a potent inhibitor of HMG-CoA reductase, IC50=40-100 nM.1 Clinically useful, orally active antihypercholesterol...$30.00 – $100.00 Select options -
Bioactive Lipids
Hymeglusin | Melvalonate biosynthesis inhibitor
Hymeglusin (29066-42-0) is an inhibitor of eukaryotic mevalonate biosynthesis via inhibition of HMG-CoA synthase, IC50=0.12 μM.1 Acts via covalent ...$215.00 – $450.00 Select options
