Metabolites
Showing 1–12 of 22 results
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Adipogenesis
20(S)-Hydroxycholesterol | Smoothened activator
20-(S)-Hydroxycholesterol (516-72-3) is an endogenous ligand for the LXR receptor.1 It has anti-adipogenic and pro-osteogenic effects in mesenchyma...$40.00 – $90.00 Select options -
Cell Death
24(S)-Hydroxycholesterol | Endogenous cholesterol metabolite
24S Hydroxycholesterol (474-73-7) is an important cholesterol metabolite (cholesterol 24-hydroxylase) found in the brain.1 It is an endogenous agon...$50.00 – $245.00 Select options -
Cholesterol
24(S),25-Epoxycholesterol | LXR agonist
24(S),25-Epoxycholesterol (77058-74-3) is a cholesterol metabolite that acts as an endogenous agonist for nuclear receptor LXR.1 Controls cellular ...$75.00 – $300.00 Select options -
Cholesterol
25-Hydroxycholesterol | Biologically active cholesterol metabolite
25 Hydroxycholesterol (2140-46-7) is a metabolite resulting from the action of cholesterol 25-hydroxylase on cholesterol. However, since cholestero...$30.00 – $105.00 Select options -
Alzheimers
27-Hydroxycholesterol | Cholesterol oxidation metabolite
27-Hydroxycholesterol (20380-11-4) is a metabolite resulting from the action of sterol 27-hydroxylase on cholesterol. Concentrations of 27-hydroxyc...$40.00 – $175.00 Select options -
Atherosclerosis
5alpha,6alpha-Epoxycholesterol | LXR ligand
5α,6α-Epoxycholesterol (1250-95-9) is a naturally occurring metabolite of cholesterol. It is a major oxysterol found in processed food1 and has be...$25.00 – $60.00 Select options -
Cholesterol
7alpha-Hydroxycholesterol | Bile acid precursor
7α-Hydroxycholesterol (566-26-7) is a metabolite resulting from the action of cholesterol 7α-hydroxylase on cholesterol. 7α-Hydroxycholesterol is t...$30.00 – $90.00 Select options -
Cholesterol
Dapansutrile | NLRP3 Inflammasome inhibitor
NLRP3i (16673-34-0) is an NLRP3 inflammasome inhibitor which likely acts via interfering with the formation of the NLRP3 inflammasome complex and w...$50.00 – $190.00 Select options -
New Products
GKT-137831 | NADPH oxidase NOX1/4 inhibitor
GKT-137831 (1218942-37-0) is an NADPH oxidase, NOX1/4 inhibitor (Ki = 100-150 nM).1 Inhibits erastin-stimulated ROS production.2 Potentiates immun...$70.00 – $280.00 Select options -
New Products
Guggulsterone-(Z) | FXR antagonist
Guggulsterone-(Z) (39025-23-5) is a natural steroid from Commiphora mukul extract (guggulipid) which lowers cholesterol and acts as an FXR antagoni...$76.00 – $300.00 Select options -
New Products
MitoBloCK-12 | Mitochondrial import inhibitor
MitoBloCK-12 (522-51-0) attenuates mitochondrial protein import (4-10 μM). Discovered in a screen of FDA-approved drugs. Blocks translocation of a ...$40.00 – $130.00 Select options -
New Products
ML335 | TREK-1,2 activator
Two-pore domain potassium (K2P) channels of the TREK subfamily regulate neuronal excitability, influence pain, temperature perception and responses...$55.00 – $220.00 Select options
