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  • Ezetimibe | Cholesterol absorption inhibitor
    Ezetimibe (163222-33-1) inhibits cholesterol absorption in the intestine by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter.1 Undergoes rapid glucuronidation in the...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of Filipin III | Cholesterol probe | CAS 480-49-9
    Filipin III (480-49-9) is a polyene macrolide antibiotic. It may be used in a double staining procedure for the detection of lipoproteins.1 Binds specifically to cholesterol forming a fluorescent complex which may be used...

  • Focus Biomolecules supplier, chemical structure of RVX-208 | BET bromodomain inhibitor | CAS 1044870-39-4
    RVX-208 (1044870-39-4) is a potent BET bromodomain antagonist with IC50 of 0.510 μM for BD2, with approximately 170-fold selectivity over BD11,2. RVX-208 increases apolipoprotein A-1 and HDL cholesterol in vitro and in...