BML-288 | PDE2 inhibitor

CAS:
851-55-3
Catalog Number:
10-1319
Activity:
PDE2 inhibitor
Chemical Name:
6,7-Dihydro-5-methyl-6-oxo-N-(1,3,4-thiadiazol-2-yl)-5H-furo[2,3-f]indole-7-carboxamide
Molecular Weight:
314.32
Molecular Formula:
C14H10N4O3S
Solubility:
Soluble in DMSO (up to 25 mg/ml)
Physical Properties:
Off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
5 mg$55.00
25 mg$220.00

BML-288 (851-55-3) is a potent and selective inhibitor of phosphodiesterase PDE2, IC50 = 40 nM. More potent than EHNA, another commonly used PDE2 inhibitor. Displays no effect on a panel of over 80 receptors, ion channels and enzymes.1 Cell permeable.

References/Citations:

1) Chambers et al. (2006), A new chemical tool for exploring the physiological function of the PDE2 isozyme; Bioorg. Med. Chem. Lett., 16 307

CAS:
851-55-3
Catalog Number:
10-1319
Activity:
PDE2 inhibitor
Chemical Name:
6,7-Dihydro-5-methyl-6-oxo-N-(1,3,4-thiadiazol-2-yl)-5H-furo[2,3-f]indole-7-carboxamide
Molecular Weight:
314.32
Molecular Formula:
C14H10N4O3S
Solubility:
Soluble in DMSO (up to 25 mg/ml)
Physical Properties:
Off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee