Adipogenesis
Showing 1–12 of 13 results
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Adipogenesis
20(S)-Hydroxycholesterol | Smoothened activator
20(S)-Hydroxycholesterol (516-72-3) is an endogenous ligand for the LXR receptor.1 It has anti-adipogenic and pro-osteogenic effects in mesenchymal...$40.00 – $90.00 Select options -
Adipogenesis
A-769662 | AMPK activator
A-769662 (844499-71-4) is a potent and reversible AMP-activated protein kinase (AMPK) allosteric activator. Activates AMPK by binding to the β and...$72.00 – $250.00 Select options -
Adipogenesis
BADGE | PPAR gamma antagonist
BADGE (1675-54-3) is a PPARγ antagonist with μM affinity in 3T3-L1 and 3T3-F442A preadipocyte cells. Selective over PPARδ and PPARα. Antagonizes th...$30.00 – $100.00 Select options -
New Products
Belumosudil | ROCK2 Inhibitor
Belumosudil (911417-87-3) is a selective inhibitor of Rho kinase 2 (ROCK2) – IC50’s: ROCK2 = 105 nM, ROCK1 = 24 µM in enzyme assays.1 It downregula...$45.00 – $145.00 Select options -
Adipogenesis
CHIR-99021 | GSK3ß inhibitor
CHIR-99021 (252917-06-9) is a potent and selective inhibitor of glycogen synthase kinase-3β (GSK3β, IC50 = 5 nM) and GSK3α (IC50 = 10 nM).1 Induces...$60.00 – $170.00 Select options -
Adipogenesis
Ciglitazone | PPARgamma agonist
Ciglitazone (74772-77-3) is a PPARγ agonist (EC50=3 μM). Stimulates adipogenesis in human mesenchymal stem cells. Ciglitazone inhibits HUVEC differ...$80.00 – $320.00 Select options -
Adipogenesis
Fatostatin | SREBP activation inhibitor
Fatostatin (125256-00-0) blocks adipogenesis by inhibiting the activation of SREBP. Inhibits the ER-Golgi translocation of SREBPs via binding to th...$50.00 – $200.00 Select options -
New Products
Honokiol | SIRT3 activator
Honokiol (35354-74-6) is a natural product that acts as a SIRT3 activator. It increases mitochondrial oxygen consumption and reduces ROS production...$55.00 – $220.00 Select options -
New Products
N-Myristoylglycine | Endogenous brown fat-inducing lipid
N-Myristoylglycine (14246-55-0) is an endogenous lipid which was found to differentiate adipocyte precursors and white-biased adipocytes into funct...$60.00 – $240.00 Select options -
New Products
NG-497 | Human ATGL inhibitor
NG-497 (2598242-66-9) is the first small molecule inhibitor (IC50 = 1 µM) of human (and rhesus monkey) adipose triglyceride lipase (ATGL). It is i...$70.00 – $260.00 Select options -
Adipogenesis
Obeticholic Acid | FXR agonist
Obeticholic acid (459789-99-2) is a novel cholic acid analog which acts as a potent and selective FXR agonist (EC50= 99 nM). Displays anticholereti...$50.00 – $200.00 Select options -
Adipogenesis
SirtAct | Sirt1 activator
SirtAct (839699-72-8) is a Sirt1 activator (233% at 10 μM)1 Suppresses TNFα release from THP-1 cells and stimulates adipogenesis in 3T3L1 cells.1 S...$80.00 – $320.00 Select options
