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  • A-769662 is a potent and reversible AMP-activated protein kinase (AMPK) allosteric activator
    A-769662 (844499-71-4) is a potent and reversible AMP-activated protein kinase (AMPK) allosteric activator.  Activates AMPK by binding to the β and γ subunits and not the AMP binding site.1 EC50=0.8 mM for...

  • AdipoRon | 924416-43-3 | Structure | Supplier
    AdipoRon (924416-43-3) is a novel potent and selective adiponectin (AdipoR1 and AdipoR2) receptor agonist, Kd=1.8 and 3.1 μM respectively1. Displayed similar effects to adiponectin in muscle and liver such as activation...

  • AICAR | 2627-69-2 | Structure | Supplier
    Activates AMP-activated protein kinase (AMPK). Promotes ligand-independent activation of the insulin receptor.1 Promotes skeletal muscle autophagy via activation of FoxO3a.2 Controls smooth muscle cell hyperproliferation in...

  • Dorsomorphin | 866405-64-3 | Structure | Supplier
    Dorsomorphin (866405-64-3) is a potent, selective and ATP-competitive inhibitor of AMP-activated protein kinase (AMPK) (Ki = 109 nM).1 It displays no significant inhibition of ZAPK, SYK, PKCT, PKA and JAK3. It inhibits bone...

  • Metformin HCl | Anti-diabetic agent
    Metformin HCl (1115-70-4) is a clinically useful antidiabetic agent. Lowers plasma glucose levels and improves insulin sensitivity. Inhibits hepatic gluconeogenesis by activation of the AMP-activated protein kinase (AMPK)...

  • Pterostilbene | Resveratrol analog
    Pterostilbene (537-42-8) is a naturally occurring stilbenoid related to resveratrol (Cat.# 10-1057). Displays antiproliferative activity. Induces accumulation of autophagic vacuoles followed by cell death in HL60 cells1...

  • Punicalagin | Anti inflammatory
    Punicalagin (65995-63-3) is a polyphenolic compound isolated from pomegranates possessing antioxidant, anti-inflammatory, and antitumorigenic properties.1,2 It has been shown to reduce high glucose-induced neural tube...

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