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  • BADGE | PPAR gamma antagonist
    BADGE (1675-54-3) is a PPARγ antagonist with μM affinity in 3T3-L1 and 3T3-F442A preadipocyte cells. Selective over PPARδ and PPARα. Antagonizes the ability of rosiglitazone to stimulate transcriptional...

  • Ciglitazone | 74772-77-3 | Structure | Supplier
    Ciglitazone (74772-77-3) is a PPARγ agonist (EC50=3 μM). Stimulates adipogenesis in human mesenchymal stem cells. Ciglitazone inhibits HUVEC differentiation and angiogenesis. Cell permeable. References/Citations1)...

  • GE-501516 | 317318-70-0 | Structure | Supplier
    GW-501516 (317318-70-0) is a potent and selective PPARδ (NR1C2) agonist, EC50=1.2 nM and 1000-fold selective over other PPAR subtypes.1  Induces apolipoprotein A1-mediated cholesterol efflux in vitro.1 Improves...

  • Oleoylethanolamide | GPR119 agonist: stimulates lipolysis
    Endogenous anandamide-like lipid acting as a PPARα agonist but does not bind to cannabinoid receptors.1 Biosynthesis via the action of NAPE-PLD on N-acylphosphatidylethanolamine.2 Agonist at GPR1193 and has been...

  • Pioglitazone | 112529-15-4 | Supplier | Structure
    Pioglitazone (112529-15-4) is a clinically useful antidiabetic drug.1 It is a selective agonist of the human peroxisome proliferator-activated receptor γ1(PPARγ1; EC50 = 490 nM2, 550nM3) with weak agonist...

  • Rosiglitazone maleate | 155141-29-0 | Structure | Supplier
    Rosiglitazone (155141-29-0) is a prototypical TZD antidiabetic agent. Potent and selective PPARg agonist (Kd=43 nM).1,2  Clinically useful antihyperglycemc agent.3  Induces a brown fat gene program in subcutaneous...

  • Troglitazone | 97322-87-7 | Structure | Supplier
    Troglitazone (97322-87-7) is a PPARγ agonist. Stimulates recruitment of transcriptional coactivators to PPARγ at 1 μM. Stimulates adipogenesis in human mesenchymal stem cells. Troglitazone induces apoptosis in...

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