2′-Deoxy-5-fluorocytidine | Irreversible DNA methyl transferase inhibitor
NMR (Conforms)
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TH10785 (1002801-51-5) is an 8-oxo guanine DNA glycosylase 1 (OGG1) activator. Oxidative DNA damage is recognized by OGG1 which then excises 8-oxoguanine, leaving a substrate for
Ochratoxin A (303-47-9) is a mycotoxin that causes widespread contamination in foodstuffs and environments thus causing health risks to humans and animals.1 It has been shown to
SR1078 (1246525-60-9) is an agonist of the orphan nuclear receptors RORα and RORγ.1 It attenuated intrapancreatic pathological changes in mouse models of chronic pancreatitis via restoration of the circadian
Isothiocyanate constituents of cruciferous vegetables are potent chemopreventive agents for carcinogen-induced cancers in rodents.1 Phenylhexyl isothiocyanate (PHITC; CAS 133920-06-6) was the most potent in a series
CBL0137 (1197996-80-7) is an anticancer agent that activates p53 and suppresses NF-kB via trapping of the FACT (facilitates chromatin transcription) complex, an important histone chaperone that mediates nucleosome
AOH1996 (2089314-64-5) inhibits proliferating cell nuclear antigen (PCNA), an enzyme critical to DNA replication and repair processes.1 It enhances the interaction between PCNA and RPB1 subunit
PF-543 (1706522-79-3) is a potent (IC50 = 2.0 nM) and selective (>100-fold over SphK2) reversible inhibitor of sphingosine kinase-1 (SphK1).1 It induced autophagy in head and neck squamous
Ochratoxin A (303-47-9) is a mycotoxin that causes widespread contamination in foodstuffs and environments thus causing health risks to humans and animals.1 It has been shown to
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