Epigenetics
Bromodomains Deubiquitinase DNA methylation Histone acetylation Histone deacetylation Histone demethylation Histone methylation Histone phosphorylation Other Epigentics
Showing 1–12 of 74 results
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Dedifferentiation
(±) Tranylcypromine hemisulfate | Demethylase inhibitor
Tranylcypromine (13492-01-8) is an irreversible and non-selective monoamine oxidase inhibitor.1,2 It has been shown to inhibit the histone demethyl...$40.00 – $150.00 Select options -
Epigenetics
(R)-PFI-2 HCl | Methyltransferase SETD7 inhibitor
(R)-PFI-2 (1627607-87-7) is a potent (IC50 = 2nM) and selective SAM-dependent inhibitor of the lysine methyltransferase SETD7.1 It alters Hippo pat...$99.00 – $375.00 Select options -
Cancer
2′-Deoxy-5-fluorocytidine | Irreversible DNA methyl transferase inhibitor
2'-Deoxy-5-fluorocytidine (10356-76-0) is a DNA methyltransferase inhibitor currently in clinical trials for breast cancer and other solid tumors1....$52.00 – $208.00 Select options -
Cancer
5-Azacytidine | DNA hypomethylation agent
5-Azacytidine (320-67-2) is specific inhibitor of DNA methyltransferase1. Incorporates into DNA and covalently reacts with and inhibits DNA methylt...$20.00 – $80.00 Select options -
Approved Drugs
6-Thioguanine | Anticancer agent / Downregulates DNMT1
6-Thioguanine (154-42-7) is a methyltransferase inhibitor. After incorporation into DNA, it disrupts cytosine methylation by DNA methyltransferase...$30.00 – $110.00 Select options -
DNA damage
A-196 | SUV420H1/H2 methyltransferase inhibitor
A-196 (1982372-88-2) is a potent and selective (over 29 other methyltransferases) inhibitor of the protein lysine methyltransferases SUV420H1(IC50 ...$70.00 – $270.00 Select options -
Bioactive Lipids
AK-7 | SIRT2 inhibitor
AK-7 (420831-40-9) is a selective Sirt2 inhibitor (IC50=15.5 μM) which does not inhibit Sirt1 or Sirt3.1 It down regulates cholesterol biosynthesis...$50.00 – $185.00 Select options -
Cancer
Anacardic Acid | HAT inhibitor
Anacardic acid (16611-84-0) is a natural product found in cashew nut oil. It is an inhibitor of the histone acetyltransferases p300 and PCAF (IC50’...$35.00 – $140.00 Select options -
Antifungals
Apicidin | HDAC inhibitor
Apicidin (183506-66-3) is a fungal toxin that is a potent, cell permeable inhibitor of histone deacetylases (HDAC's).1 It also displays antitumor p...$55.00 – $220.00 Select options -
Cardiovascular
AS-8351 | KDM5B histone demethylase inhibitor
AS-8351 (796-42-9) has been used in a cocktail of nine small molecules used to efficiently induce cardiac reprogramming of human fibroblasts.1 It i...$50.00 – $200.00 Select options -
Epigenetics
BIX-01294 | Histone Methyltransferase inhibitor
BIX-01294 (935693-62-2) is a selective inhibitor of G9a histone methyltransferase (G9aHMTase; IC50 = 1.7 μM) as well as GLP HMTase (IC50 = 38 μM) l...$60.00 – $240.00 Select options -
Epigenetics
BML-210 | HDAC inhibitor
BML-210 (537034-17-6) is a novel non-hydroxamic acid HDAC inhibitor. IC50=5-10 μM (HeLa nuclear extract). Induces growth inhibition, proapoptotic a...$50.00 – $200.00 Select options
