BML-210 | HDAC inhibitor

CAS:
537034-17-6
Catalog Number:
10-2366
Activity:
HDAC inhibitor
Chemical Name:
N1-(2-Aminophenyl)-N8-phenyloctanediamide
Molecular Weight:
339.44
Molecular Formula:
C20H25N3O2
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 10 mg/ml with warming)
Physical Properties:
Tan solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
5 mg$60.00
25 mg$240.00

BML-210 (537034-17-6) is a novel non-hydroxamic acid HDAC inhibitor. IC50=5-10 μM (HeLa nuclear extract). Induces growth inhibition, proapoptotic and differentiation effects on human leukemia cell lines.

References/Citations:

1) Savickiene, et al. (2006), The novel histone deacetylase inhibitor BML-210 exerts growth inhibitory, proapoptotic and differentiation stimulating effects on the human leukemia cell lines; Eur. J. Pharmacol. 549 9
2) Herman, et al. (2006), Histone deacetylase inhibitors reverse gene silencing in Friedreich’s ataxia; Nat. Chem. Biol. 10 551

CAS:
537034-17-6
Catalog Number:
10-2366
Activity:
HDAC inhibitor
Chemical Name:
N1-(2-Aminophenyl)-N8-phenyloctanediamide
Molecular Weight:
339.44
Molecular Formula:
C20H25N3O2
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 10 mg/ml with warming)
Physical Properties:
Tan solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee