Bromodomains
Showing all 11 results
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New Products
BI 2536 | Dual Plk/BRD4 inhibitor – Destabilizes Myc
BI 2536 (755038-02-9) was originally reported as a potent (IC50’s Plk1 = 0.83nM, Plk2 = 3.5nM and Plk3 = 9.0nM)1 and selective2 Polo-like kinase in...$75.00 – $275.00 Select options -
New Products
BI-9564 | BRD9 bromodomain inhibitor
BI-9564 (1883429-22-8) is a potent, selective, and cell permeable inhibitor of the BRD9 bromodomain, a subunit of the switch/sucrose nonfermentable...$60.00 – $195.00 Select options -
Bromodomains
Bromosporine | Pan-bromodomain inhibitor
Bromosporine (1619994-69-2) is a potent pan-Bromodomain (BRD) inhibitor.1 Bromosporine was able to reactivate HIV-1 replication in different latenc...$80.00 – $275.00 Select options -
New Products
BZ1 | BPTF inhibitor
BZ1 (2766623-38-3) is a potent (Kd = 6.3 nM; IC50 = 67 nM BPTF Alphascreen) inhibitor of the bromodomain PHD finger transcription factor (BPTF). I...$65.00 – $250.00 Select options -
New Products
GSK6853 | BRPF1 inhibitor
GSK6853 (1910124-24-1) is a very potent (pIC50 = 8.6 vs full length protein, 7.7 in cellular assays) inhibitor of Bromodomain and PHD Finger-contai...$65.00 – $250.00 Select options -
Bromodomains
I-BET762 | BET Bromodomain inhibitor / Suppresses Myc transcription
I-BET762 (1260907-17-2) is a potent inhibitor of the BET family of bromodomains with no activity at bromodomains BAZ2B, SP140, ATAD2, CREBBO, and P...$70.00 – $295.00 Select options -
New Products
JQ1 (+) | BET Bromodomain inhibitor
JQ1 (+) (1268524-70-4) is a potent BET bromodomain inhibitor and is the active isomer. IC50 = 17.7, 32.6, 76.9 and 12942 nM respectively for BRD2...$100.00 – $400.00 Select options -
Bromodomains
JQ1 | Bromodomain inhibitor
(±) JQ1 (1268524-69-1) is a potent BET bromodomain inhibitor. IC50 = 17.7, 32.6, 76.9 and 12942 nM respectively for BRD2 (N-terminal (N)), BRD4 (C-...$65.00 – $260.00 Select options -
New Products
PFI-3 | Selective Bromodomain family VIII inhibitor
PFI-3 (1819363-80-8) is a selective inhibitor of family VIII bromodomains PB1(5), SMARCA2, and SMARCA4.1 It showed complete selectivity over all no...$59.00 – $215.00 Select options -
Atherosclerosis
RVX-208 | BET bromodomain inhibitor
RVX-208 (1044870-39-4) is a potent BET bromodomain antagonist with IC50 of 0.510 μM for BD2, with approximately 170-fold selectivity over BD1.1,2 R...$68.00 – $272.00 Select options -
New Products
Volasertib | Potent and selective inhibitor of Polo-like kinase 1
Volasertib (755038-65-4) is an extremely potent and selective inhibitor (IC50’s: Plk1= 0.87 nM, Plk2 = 5 nM, Plk3 = 56 nM) of Polo-like kinase 1, a...$80.00 – $275.00 Select options
