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Bromodomains

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  • Bromosporine | Pan-bromodomain inhibitor
    Bromosporine | Pan-bromodomain inhibitor
    $90.00
    Bromosporine (1619994-69-2) is a potent pan-Bromodomain (BRD) inhibitor.1 Bromosporine was able to reactivate HIV-1 replication in different latency models.2 References/Citations 1) Picaud et al. (2016), Promiscuous...

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  • Focus Biomolecules cell signaling supplier, chemical structure of I-BET762 | BET Bromodomain inhibitor | CAS 1260907-17-2
    I-BET762 | BET Bromodomain inhibitor / Suppresses Myc transcription
    $70.00
    I-BET762 (1260907-17-2) is a potent inhibitor of the BET family of bromodomains with no activity at bromodomains BAZ2B, SP140, ATAD2, CREBBO, and PCAF.1,2 IC50’s for H4Ac peptide displacement: BRD2 = 32.5nM, BRD3 = 42...

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  • Focus Biomolecules cell signaling reagent supplier, chemical structure of JQ1 | Bromodomain inhibitor | CAS 1268524-69-1
    JQ1 | Bromodomain inhibitor
    $65.00
    (±) JQ1 (1268524-69-1) is a potent BET bromodomain inhibitor. IC50 = 17.7, 32.6, 76.9 and 12942 nM respectively for BRD2 (N-terminal (N)), BRD4 (C-terminal (C)), BRD4 (N) and CREBBP respectively. Competitive binding...

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  • Focus Biomolecules supplier, chemical structure of RVX-208 | BET bromodomain inhibitor | CAS 1044870-39-4
    RVX-208 | BET bromodomain inhibitor
    $68.00
    RVX-208 (1044870-39-4) is a potent BET bromodomain antagonist with IC50 of 0.510 μM for BD2, with approximately 170-fold selectivity over BD11,2. RVX-208 increases apolipoprotein A-1 and HDL cholesterol in vitro and in...

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