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CPTH2 | HAT inhibitor

CPTH2 (357649-93-5) is a selective inhibitor of the histone acetyltransferase Gcn5P both in vitro and in vivo (IC50 = 0.8 mM). In vitro, the HAT inhibitory activity of CPTH2 was caused via bridge-interaction with histone H3. It’s in vivo activity may involve more histonic and/or non-histonic Gcn5p substrates.

References/Citations:

1) Chimenti et al. (2009), A novel histone acetyltransferase inhibitor modulating Gcn5 network: cyclopentylidene-[4-(4′-chlorophenyl)thiazol-2-yl]hydrazone); J. Med .Chem., 52 530

Weight 0.01 mg
Dimensions 0.01 × 0.01 × 0.01 cm
Size :

5 mg, 25 mg

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CAS:
357649-93-5
Catalog Number:
10-4528
Activity:
HAT inhibitor
Chemical Name:
Cyclopentylidene-[4-(4′-chlorophenyl)thiazol-2-yl]hydrazone
Molecular Weight:
291.8
Molecular Formula:
C14H14ClN3S
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Shipping Code:
RT

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CPTH2 | HAT inhibitor

$69.00 – $250.00

CAS:
357649-93-5
Catalog Number:
10-4528
Activity:
HAT inhibitor
Chemical Name:
Cyclopentylidene-[4-(4′-chlorophenyl)thiazol-2-yl]hydrazone
Molecular Weight:
291.8
Molecular Formula:
C14H14ClN3S
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Shipping Code:
RT
  • 5 mg
  • 25 mg
Clear
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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