DNA methylation
Showing all 8 results
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Cancer
2′-Deoxy-5-fluorocytidine | Irreversible DNA methyl transferase inhibitor
2'-Deoxy-5-fluorocytidine (10356-76-0) is a DNA methyltransferase inhibitor currently in clinical trials for breast cancer and other solid tumors1....$52.00 – $208.00 Select options -
Cancer
5-Azacytidine | DNA hypomethylation agent
5-Azacytidine (320-67-2) is specific inhibitor of DNA methyltransferase1. Incorporates into DNA and covalently reacts with and inhibits DNA methylt...$20.00 – $80.00 Select options -
Approved Drugs
6-Thioguanine | Anticancer agent / Downregulates DNMT1
6-Thioguanine (154-42-7) is a methyltransferase inhibitor. After incorporation into DNA, it disrupts cytosine methylation by DNA methyltransferase...$30.00 – $110.00 Select options -
Approved Drugs
Decitabine | DNA hypomethylation agent
Decitabine (2353-33-5) inhibits DNA methyltransferase. Induces demethylation and reactivation of silenced genes. Increases stem cell reprogramming ...$60.00 – $200.00 Select options -
Cancer
Mithramycin A | Transcription inhibitor
Mithramycin A (18378-89-7) inhibits DNA methyl transferase.1 A selective Sp1 inhibitor, it binds to GC rich DNA sequences, displacing Sp1 transcrip...$40.00 – $160.00 Select options -
Cancer
PF-9366 | Methionine adenosyltransferase 2A inhibitor
PF-9366 (72882-78-1) is an allosteric inhibitor (IC50 = 420 nM) of methionine adenosyltransferase 2A (Mat2A), the primary enzyme responsible for ex...$70.00 – $265.00 Select options -
Dedifferentiation
RG-108 | DNA Methyltransferase inhibitor
RG-108 (48208-26-0) is a non-nucleoside DNA methyltransferase inhibitor. IC50=115 nM1 Inhibits DNA methylation in human tumor cell lines without to...$40.00 – $160.00 Select options -
Angiogenesis
Zebularine | DNA methylation inhibitor
Zebularine (3690-10-6) is an orally active DNA methyltransferase inhibitor. Inhibits tumor cell proliferation (IC50 = 120 μM) and re-activates sile...$50.00 – $190.00 Select options
