Histone demethylation
Showing 13–16 of 16 results
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Antivirals
ML324 | JMJD2 inhibitor
ML324 (1222800-79-4) inhibits JMJD2 histone demethylases. Represses the expression of viral (HCMV and HSV-1) immediate early genes (IC50 ~ 10 μM) a...$50.00 – $180.00 Select options -
Cancer
PBIT | JARID1 lysine demethylase inhibitor
PBIT (2514-30-9) is a potent and selective inhibitor of JARID1 (IC50 = 3, 4.9 and 6 μM for JARID1B, 1A and 1C, respectively). The JARID1 (Jumonji A...$62.00 – $240.00 Select options -
Apoptosis
SP2509 | LSD1 inhibitor
SP2509 (1423715-09-6) is a potent (IC50 = 13 nM) and reversible inhibitor of the histone demethylase LSD1 (KDM1A).1 It is inactive against the clos...$70.00 – $270.00 Select options -
New Products
TETi76 ester | TET inhibitor
TETi76 ester (1451750-73-4) is a cell permeable inhibitor of TET dioxygenases (IC50s: TET1 = 1.5 µM; TET2 = 9.4 µM; TET3 = 8.8 µM), indirect (via ...$75.00 – $275.00 Select options
