Histone methylation
Showing 1–12 of 14 results
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Epigenetics
(R)-PFI-2 HCl | Methyltransferase SETD7 inhibitor
(R)-PFI-2 (1627607-87-7) is a potent (IC50 = 2nM) and selective SAM-dependent inhibitor of the lysine methyltransferase SETD7.1 It alters Hippo pat...$99.00 – $375.00 Select options -
DNA damage
A-196 | SUV420H1/H2 methyltransferase inhibitor
A-196 (1982372-88-2) is a potent and selective (over 29 other methyltransferases) inhibitor of the protein lysine methyltransferases SUV420H1(IC50 ...$70.00 – $270.00 Select options -
Epigenetics
BIX-01294 | Histone Methyltransferase inhibitor
BIX-01294 (935693-62-2) is a selective inhibitor of G9a histone methyltransferase (G9aHMTase; IC50 = 1.7 μM) as well as GLP HMTase (IC50 = 38 μM) l...$60.00 – $240.00 Select options -
Apoptosis
Chaetocin | Lys methyltransferase inhibitor
Chaetocin (28097-69-1) is an antimicrobial fungal metabolite. Selective inhibitor of lysine specific histone methtransferase1. Chaetocin has an ant...$40.00 – $168.00 Select options -
Angiogenesis
DZNep | Methyltransferase inhibitor
DZNep (102052-95-9) is a potent histone methyltransferase inhibitor which decreases global histone methylation.1 Inhibits trimethylation of H3K27 a...$142.00 – $550.00 Select options -
Cancer
EED-226 | PRC2 methyltransferase inhibitor
EED-226 (2083627-02-3) is a potent (IC50 = 23.4 nM) and selective allosteric inhibitor of the EED subunit of the methyltransferase polycomb repres...$85.00 – $285.00 Select options -
Cancer
EPZ015666 | Potent and selective PRMT5 inhibitor
EPZ015666 (1616391-65-1) is a selective and potent (IC50 = 22nM) inhibitor of arginine methyltransferase 5 (PRMT5).1,2 PRMT5 inhibition with EPZ015...$110.00 – $395.00 Select options -
Cancer
GSK3326595 | Selective PRMT5 inhibitor
GSK3326595 (1616395-22-3) is a potent (IC50 = 6.2nM), selective (>4000-fold over 20 other methyltransferases), SAM uncompetitive, peptide compet...$50.00 – $195.00 Select options -
Cancer
PF-9366 | Methionine adenosyltransferase 2A inhibitor
PF-9366 (72882-78-1) is an allosteric inhibitor (IC50 = 420 nM) of methionine adenosyltransferase 2A (Mat2A), the primary enzyme responsible for ex...$70.00 – $265.00 Select options -
Epigenetics
Sinefungin | Methyltransferase inhibitor
Sinefungin (58944-73-3) is a nucleoside S-adenosyl-1-methionine analog. Potent, competitive methyltransferase (protein, DNA, and RNA methyltransfer...$60.00 – $240.00 Select options -
New Products
Tazemetostat | EZH2 inhibitor
Tazemetostat (1403254-99-8) is a potent (Ki = 2.5nM wild type human PRC2-containing) and selective SAM-competitive inhibitor of the lysine methyltr...$55.00 – $175.00 Select options -
Cancer
TC-E 5003 | Arginine methyltransferase 1 (PRMT1) inhibitor
TC-E 5003 (17328-16-4) is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor, IC50 = 1.5 μM. Displays no activity against CARM1 and...$60.00 – $240.00 Select options
