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ML324 | JMJD2 inhibitor

ML324 (1222800-79-4) inhibits JMJD2 histone demethylases. Represses the expression of viral (HCMV and HSV-1) immediate early genes (IC50 ~ 10 μM) and abrogates infection. ML-324 represses the reactivation of HSV from the latent state in sensory neurons.1

References/Citations:

1) Liang et al. (2013), Targeting the JMJD2 histone demethylases to epigenetically control herpesvirus infection and reactivation from latency; Sci. Transl. Med., 5 167ra5

Weight 0.01 mg
Dimensions 0.01 × 0.01 × 0.01 cm
size :

5 mg, 25 mg

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CAS:
1222800-79-4
Catalog Number:
10-1455
Activity:
JMJD2 inhibitor
Chemical Name:
N-(3-(Dimethylamino)propyl)-4-(8-hydroxyquinolin-6-yl)benzamide
Molecular Weight:
349.43
Molecular Formula:
C21H23N3O2
Solubility:
Soluble in DMSO (10 mg/ml).
Physical Properties:
Off-white to pale yellow solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Shipping Code:
RT

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ML324 | JMJD2 inhibitor

$50.00 – $180.00

CAS:
1222800-79-4
Catalog Number:
10-1455
Activity:
JMJD2 inhibitor
Chemical Name:
N-(3-(Dimethylamino)propyl)-4-(8-hydroxyquinolin-6-yl)benzamide
Molecular Weight:
349.43
Molecular Formula:
C21H23N3O2
Solubility:
Soluble in DMSO (10 mg/ml).
Physical Properties:
Off-white to pale yellow solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Shipping Code:
RT
  • 5 mg
  • 25 mg
Clear
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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