Extracellular matrix and adhesion
Showing all 12 results
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Aminopeptidases
Actinonin | Leucyl aminopeptidase inhibitor
Actinonin (13434-13-4) is a potent hydroxamic acid inhibitor of aminopeptidases which displays analgesic effects by inhibiting enkephalin-degrading...$35.00 – $140.00 Select options -
Bone and Connective Tissue
Ansatrienin B | Cytotoxic activity
Ansatrienin b (82189-04-6) represents a novel class of ansamycins.1 Inhibits osteoclastic bone resorption.2 Potentiates the activity of several cli...$345.00 Select options -
Cell adhesion
BAY 11-7082 | IKK inhibitor
BAY 11-7082 (19542-67-7) inhibits cytokine-induced IκB-α phosphorylation via inhibition of IκB Kinase which results in inhibition of NFκB 1. Inhibi...$60.00 – $200.00 Select options -
Cancer
CL-82198 | MMP-13 inhibitor
CL-82198 (307002-71-7) is a selective inhibitor of MMP-13 (IC50 = 10 μM). It displayed no activity against MMP-1, MMP-9 or TACE. References/Cita...$50.00 – $200.00 Select options -
Angiogenesis
FAK inhibitor 14 | FAK inhibitor
FAK inhibitor 14 (4506-66-5) is a selective focal adhesion kinase (FAK) inhibitor that displays no significant activity at a range of other kinases...$45.00 – $180.00 Select options -
Approved Drugs
Fasudil HCl | ROCK inhibitor
Fasudil HCl (105628-07-7) is a Rho-associated kinase inhibitor (IC50 = 1.9 μM and 10.7 μM for Rho-associated kinase II and Rho-associated kinase re...$45.00 – $150.00 Select options -
Extracellular matrix and adhesion
Ilomastat (GM-6001) | MMP inhibitor
Ilomastat (142880-36-2) is a potent pan-specific inhibitor of matrix metalloproteinases (MMPs).1 Ki values have been reported for the following hum...$48.00 – $192.00 Select options -
Extracellular matrix and adhesion
NNGH | MMP inhibitor (pan specific)
NNGH (161314-17-6) is a potent pan-specific inhibitor of matrix metalloproteinases ( MMP3 Ki=0.013 μM). Inhibits MMP-1, -2, -7-10, -12-14 and MMP-2...$55.00 – $220.00 Select options -
Angiogenesis
Sphingosine-1-phosphate | EDG receptor ligand
Sphingosine-1-phosphate (26993-30-6) is an endogenous sphingolipid metabolite known to be involved in many cellular responses including angiogenesi...$65.00 – $240.00 Select options -
New Products
Thiolutin | Inhibitor of the DUB PSMD14
Thiolutin (87-11-6) inhibits the deubiquitinating (DUB) activity of PSMD14 exhibiting potent antitumor activity in neck squamous cell carcinoma in ...$60.00 – $186.00 Select options -
ALS
WHI-P131 | JAK3 inhibitor
WHI-P131 (202475-60-3) is a JAK3 inhibitor. Inhibits human glioblastoma cell adhesion and invasion.1 Increases survival in a mouse ALS model.2 Dela...$50.00 – $200.00 Select options -
Differentiation
Y-27632 dihydrochloride | ROCK family kinase inhibitor
Y-27632 dihydrochloride (129830-38-2) is a specific inhibitor of ROCK family kinases.1 Enhances stem cell survival and proliferation in culture.2 Y...$40.00 – $175.00 Select options
