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  • Focus Biomolecules cell signaling reagent supplier, structure of 3-Aminobenzamide | PARP inhibitor | CAS 3544-24-9
    3-Aminobenzamide (3544-24-9) inhibits endogenous poly-ADP-ribosyltransferases1. Inhibits nitric oxide-induced apoptosis but not differentiation in HL-60 cells2. Inhibits stress-induced apoptosis3. 3-Aminobenzamide has been...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of ME-0328 | PARP3 inhibitor | CAS 1445251-22-8
    ME-0328 (1445251-22-8) is a potent and selective PARP3 inhibitor (IC50=0.89 μM). Selective over PARP-1, PARP-2 and other ARDT enzymes (IC50=6.3, 10.8 and >30 μM respectively) References/Citations1) Lindgren et al...

  • Olaparib | PARP1 inhibitor
    Olaparib (763113-22-0) is a highly potent and selective PARP-inhibitor with IC50 values of 5 nM and 1 nM for PARP-1 and PARP-2, respectively.1  In a genetically engineered mouse model for BRCA1-associated breast cancer...

  • PJ-34 HCl | PARP1,2 inhibitor
    PJ-34 HCl (344458-15-7) is a potent and selective inhibitor of PARP1 and 2. EC50 = 20 nM1. Reduces ischemia reperfusion injury in a mouse model.2 Displays anti-inflammatory effects in a transient focal cerebral ischemia...

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