9-Hydroxyrisperidone | Risperidone metabolite

CAS:
144598-75-4
Catalog Number:
10-2300
Activity:
Risperidone metabolite
Chemical Name:
3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
Alternate Name:
Paliperidone
Molecular Weight:
426.48
Molecular Formula:
C23H27FN4O3
Solubility:
Soluble in DMSO (up to 4 mg/ml).
Physical Properties:
White solid
Purity:
95% by HPLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
Shipping Code:
RT

Available Options

Size:PriceQuantity 
10 mg$30.00
50 mg$110.00

9-Hydroxyrisperidone (144598-75-4) is a pharmacologically active metabolite of risperidone, an atypical antipsychotic agent.1 Displays high affinity for serotonin 5-HT2A receptors as well as dopamine D2 receptors.2,3

References/Citations:

1) Beijsterveldt et al. (1994), Regional brain distribution of risperidone and its active metabolite 9-hydroxy-risperidone in the rat; Psychopharmacology, 114 53
2) Leysen et al. (1994), Risperidone: a novel antipsychotic with balanced serotonin-dopamine antagonism, receptor occupancy profile, and pharmacologic activity; J. Clin. Psychiatry, 55 suppl: 5
3) Schotte et al. (1996), Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding; Psychopharmacology (Berl.), 124 57

CAS:
144598-75-4
Catalog Number:
10-2300
Activity:
Risperidone metabolite
Chemical Name:
3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
Alternate Name:
Paliperidone
Molecular Weight:
426.48
Molecular Formula:
C23H27FN4O3
Solubility:
Soluble in DMSO (up to 4 mg/ml).
Physical Properties:
White solid
Purity:
95% by HPLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

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