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  • Focus Biomolecules supplier, chemical structure of CL-316243 | beta 3-adrenergic agonist / antiobesity | CAS 151126-84-0
    CL-316243 (151126-84-0) is a potent and selective β-3 adrenergic receptor agonist. (EC50= 3 nM) Displays anti-obesity and anti-diabetic effects in mice. It increases brown fat thermogenesis and metabolic rate and...

  • Focus Biomolecules supplier, chemical structure of Efaroxan HCl | alpha 2 adrenergic antagonist | CAS 89197-00-2
    Efaroxan HCl (89197-00-2) is a selective α2-adrenergic receptor antagonist1 (selectivity ratio of α2/α1 = 724)4 and imidazoline receptor antagonist2. Induces release of insulin in the rat insulinoma cell...

  • Perphenazine | Antipsychotic agent
    Perphenazine (58-39-9) is a clinically useful typical antipsychotic drug.  The therapeutic mode of action is not well understood but it binds to a wide variety of receptors including serotonin, histamine, dopamine, and...

  • Focus Biomolecules cell signaling reagent supplier, structure Phenoxybenzamine HCl | Calmodulin antagonist | CAS 63-92-3
    Phenoxybenzamine HCl (63-92-3) binds to and inhibits calmodulin in a calcium-dependent and irreversible manner (IC50= ca. 1 μM)1. A classical irreversible α adrenergic antagonist2. Phenoxybenzamine HCl is a useful...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure SCH-202676 | G-protein inhibitor | CAS 70375-43-8
    SCH-202676 (70375-43-8) is a reversible inhibitor of both agonist and antagonist binding to G protein-coupled receptors (GPCRs).1 IC50's = 0.1-1.7 μM for nine GPCRs.1 Modification of GPCRs is accomplished via sulfhydryl...

  • Terazocin HCl | Adrenergic antagonist
    Terazocin HCl (63074-08-8) is an α1- and α2B-adrenoceptor antagonist (Ki = 3.3, 0.7, 1.1, 7.7, 1510 and 78.2 nM for α1A, α1B, α1D, α2B, α2A and α2C receptors respectively)1...

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