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  • Allopregnanolone | GABA-A positive allosteric modulator
    Allopregnanolone (516-54-1) is an endogenous neurosteroid which acts as a positive allosteric modulator of GABAA receptors.1,2 Recently FDA approved (Brexanolone) for postpartum depression.3 Inhibits TLR4 receptor activation...

  • Flupirtine maleate | K+ channel activator
    flupirtine maleate (75507-68-5) activates KV7 potassium channels1, indirectly antagonizes NMDA receptors and modulates GABAA receptors2. Displays neuroprotective actions in a model of cerebral ischemia in mice and reduces...

  • Focus Biomolecules cell signaling reagent supplier, structure of Gaboxadol HCl | GABA-A receptor agonist | CAS 64603-91-4
    Gaboxadol HCl (64603-91-4) is a GABAA receptor agonist. Hypnotic agent. References/Citations1) Meera et al. (2011), Molecular basis for the high THIP/gaboxadol sensitivity of extrasynaptic GABA(A) receptors; J. Neurophysiol...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of Muscimol HBr | GABA-A agonist | CAS 18174-72-6
    Muscimol HBr (18174-72-6) is a GABA-A receptor agonist. References/Citations 1) Akhondzadeh et al. (1995), Induction of a novel form of hippocampal long-term depression by muscimol: involvement og GABAA but not glutamate...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of Theanine | GABA agonist | CAS 3081-61-6
    L-Theanine (3081-61-6) is a naturally occurring amino acid found in tea leaves. It is able to cross the blood brain barrier and has been shown to have psychoactive effects1 including cognition improvement, reduction of...

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