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  • Focus Biomolecules cell signaling supplier, chemical structure of Cinnabarinic acid | Endogenous AhR ligand | CAS 606-59-7
    Cinnabarinic acid (606-59-7) is a novel endogenous tryptophan metabolite which acts as an aryl hydrocarbon receptor (AHR) agonist.1 It drives IL-22 production by stimulating the differentiation of human and mouse T cells...

  • Focus Biomolecules reagent supplier, chemical structure Cycloserine, D(+) | NMDA, glycine site partial agonist | CAS 68-41-7
    D-Cycloserine (68-41-7) is a partial agonist at the glycine modulatory site of NMDA glutamatergic receptors.1 Blocks kainate-induced seizures2 and displays anticonvulsant effects3 in rat models. D-Cycloserine facilitates...

  • Flupirtine maleate | K+ channel activator
    flupirtine maleate (75507-68-5) activates KV7 potassium channels1, indirectly antagonizes NMDA receptors and modulates GABAA receptors2. Displays neuroprotective actions in a model of cerebral ischemia in mice and reduces...

  • Focus Biomolecules cell signaling supplier, chemical structure of Ibotenic acid | NMDA & mGluR agonist | CAS 2552-55-8
    Ibotenic acid (60573-88-8) is a conformationally restricted analog of glutamate which occurs naturally in Amanita mascaria and related mushrooms.  It is a non-specific glutamate receptor (both NMDA and mGluR) agonist.1...

  • Focus Biomolecules supplier, chemical structure of Kainic acid | Kainate receptor agonist; neurotoxin |  CAS 487-79-6
    Kainic acid (487-79-6) is a conformationally restricted glutamate analog which acts as a selective agonist at kainate receptors. CNS stimulant and neurotoxin. Kainic acid is a classic neuroexcitatory agent for induction of...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of MDL29,951 | GPR17 activator | CAS 130798-51-5
    MDL29,951 (130798-51-5) is a new, highly specific, small molecule activator of GPR171 that has been shown to be active in intact cells1. The ability to specifically activate GPR17 allows for the study of the exact role GPR17...

  • Focus Biomolecules cell signaling supplier, chemical structure of MPEP HCl | mGlu5 Receptor antagonist | CAS 219911-35-0
    MPEP HCl (219911-35-0) is a potent (IC50 = 36 nM for quisqualate-stimulated phosphoinositide hydrolysis) and selective (over mGlu1b, -2, -3, -4a, -6, -7b, and -8a) antagonist of the metabotropic glutamate receptor subtype 5...

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