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  • Focus Biomolecules cell signaling reagent supplier, chemical structure LY-171883 | Cys LT1 antagonist | CAS 88107-10-2
    LY-171883 (88107-10-2) is a selective and orally active leukotriene D4 (LTD4) antagonist (Ki = 0.63 μM).1 It is also an activator of peroxisome proliferator-activated receptors (PPAR's).2,3 References/Citations1) Fleisch...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of MK-571 | Cys LT1 antagonist | CAS 115104-28-4
    MK-571 (115104-28-4) is a potent (EC50 = 1.3nM) and selective Leukotriene D4 antagonist (LTD4)1 displaying inverse agonist activity2. Blocks binding of LTD4 to human (Ki = 0.22 nM) and guinea pig (Ki = 2.1 nM) lung membranes...

  • Focus Biomolecules supplier, chemical structure of Montelukast sodium | Leukotriene & GPR17 antagonist | CAS 151767-02-1
    Montelukast sodium (151767-02-1) is a potent, selective CysLT1 receptor (leukotriene D4) antagonist (Ki = 0.18 nM).1,2 Displays anti-inflammatory and anti-asthmatic effects. Clinically useful agent for treatment of chronic...

  • Focus Biomolecules offers cell signaling reagent, Zafirlukast | HSP70 inhibitor, leukotriene antagonist | CAS 107753-78-6
    Zafirlukast (107753-78-6) is a competitive and selective leukotriene receptor antagonist1. Also inhibits calcium ionophore induced production of leukotriene B4 and leukotriene C4, which suggests a potential 5-LO inhibitory...