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Serotonin

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  • Focus Biomolecules cell signaling reagent supplier, chemical structure Clozapine | Dopamine D2/D4 antagonist | CAS 5786-21-0
    $30.00
    Clozapine (5786-21-0) is a dopamine D4 and D2 receptor antagonist. High affinity for the cloned rat dopamine D4 receptor (Ki < 20 nM).1 Atypical neuroleptic agent.2 Antagonist at 5HT2A, 5HT2C, 5HT3, 5HT6 and 5HT7...

  • Fluoxetine HCl | Serotonin reuptake inhibitor
    $50.00
    Fluoxetine HCl (56296-78-7) is a selective serotonin reuptake inhibitor (SSRI) with high selectivity for the serotonin transporter (Kd=0.81 nM) over the norepinephrine (Kd=240 nM) and dopamine (Kd=3.6 mM) transporters.1 A...

  • Focus Biomolecules cell signaling supplier, chemical structure of Lomerizine | Calcium channel blocker | CAS 101477-54-7
    $40.00
    Lomerizine (101477-54-7) is a clinically useful calcium channel blocker (L and T-type).  It is used for the treatment of migraine headaches, however its antimigraine effects are believed to be due to its 5HT2A...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of Perphenazine | Antipsychotic agent | CAS 58-39-9
    $25.00
    Perphenazine (58-39-9) is a clinically useful typical antipsychotic drug. The therapeutic mode of action is not well understood but it binds to a wide variety of receptors including serotonin, histamine, dopamine, and...

  • Focus Biomolecules supplier, chemical structure of Quetiapine hemifumarate | Atypical antipsychotic agent | CAS 111974-72-2
    $30.00
    Quetiapine hemifumarate (111974-72-2) is an atypical antipsychotic agent. Antagonist at serotonin (5-HT2) and dopamine (D2) receptors, IC50s=148 and 329 nM respectively.2 Reverses depressive-like behavior and reduces DNA...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of Terguride | Dopamine D2 agonist | CAS 37686-84-3
    $125.00
    Terguride (37686-84-3) is a semi-synthetic ergoline derivative which acts as a partial dopamine D2 agonist and 5HT2B/2C receptor antagonist. Displays antiparkinsonian effects in MPTP-treated cynomolgus monkeys1. Partial...

  • Focus Biomolecules supplier, chemical structure of Tianeptine sodium salt | Neuroprotective agent | CAS 30123-17-2
    $40.00
    Tianeptine sodium salt (30123-17-2) is a selective enhancer of serotonin uptake in the brain with no effect on noradrenalin or dopamine uptake.1 Clinically useful antidepressant.2 Displays neuroprotective effects against...

  • Focus Biomolecules supplier, chemical structure of Zolmitriptan | Serotonin 5HT1B/1D receptor agonist | CAS 139264-17-8
    $50.00
    Zolmitriptan (CAS 139264-17-8) is a potent and selective serotonin 5HT 1B/1D agonist (Ki=0.63 and 5.01 nM for 5HT 1D and 1B respectively.1 Displays proven efficacy for the treatment of migraine.2 Inhibits neurogenic...

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